BMC Genomics, 2010 Background Computational methods for identifying selenoproteins have been developed rapidly in recent years. However, it is still difficult to identify the open reading frame (ORF) of eukaryotic selenoprotein gene, because the TGA codon for a ...
Jiang Liang, Liu Qiong, Ni Jiazuan
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Sea squirt alternative oxidase bypasses fatal mitochondrial heart disease [PDF]
EMBO Molecular Medicine, 2018 Mitochondrial diseases are a diverse group of inborn disorders affecting cellular energy production by oxidative phosphorylation (OXPHOS) via the five (CI‐CV) mitochondrial respiratory chain (MRC) complexes.
Ann Saada
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The genome sequence of Aplidium turbinatum (Savigny 1816), a colonial sea squirt [version 1; peer review: 2 approved] [PDF]
Wellcome Open Research, 2022 We present a genome assembly from an individual Aplidium turbinatum (Chordata; Ascidiacea; Aplousobranchia; Polyclinidae). The genome sequence is 605 megabases in span.
John Bishop +2 more
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Aqueous Extract of Sea Squirt (Halocynthia roretzi) with Potent Activity against Human Cancer Cells Acts Synergistically with Doxorubicin [PDF]
Marine Drugs, 2022 Marine ascidian is becoming one of the main sources of an antitumor drug that has shown high bioactivity and extensive application in cancer treatment.
Yuting Zhu +4 more
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Sea Squirt-Derived Peptide WLP Mitigates OKA-Induced Alzheimer’s Disease-like Phenotypes in Human Cerebral Organoid [PDF]
AntioxidantsAlzheimer’s disease (AD), a prevalent neurodegenerative disorder in the elderly, poses significant humanistic and economic burdens worldwide. Previously, we identified Trp-Leu-Pro (WLP), a novel antioxidant peptide derived from the sea squirt ...
Qiqi Chen +12 more
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A Novel Carotenoid with a Unique 2,6-Cyclo-ψ-End Group, Roretziaxanthin, from the Sea Squirt Halocynthia roretzi [PDF]
Marine Drugs, 2022 A novel carotenoid with a unique 2,6-cyclo-ψ-end group, named roretziaxanthin (1), was isolated from the sea squirt Halocynthia roretzi as a minor carotenoid along with (3S,3′S)-astaxanthin, alloxanthin, halocynthiaxanthin, mytiloxanthin ...
Takashi Maoka, Chisato Tode
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The genome sequence of the light-bulb sea squirt, Clavelina lepadiformis (Müller, 1776) [version 1; peer review: 2 approved] [PDF]
Wellcome Open Research, 2023 We present a genome assembly from an individual Clavelina lepadiformis (the light-bulb sea squirt; Chordata; Ascidiacea; Aplousobranchia; Clavelinidae). The genome sequence is 210.1 megabases in span. Most of the assembly is scaffolded into 9 chromosomal
John Bishop +3 more
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The genome sequence of a solitary sea squirt, Ascidia mentula (Müller, 1776) [version 1; peer review: 2 approved] [PDF]
Wellcome Open Research, 2023 We present a genome assembly from an individual Ascidia mentula (the (a solitary sea squirt); Chordata; Ascidiacea; Phlebobranchia; Ascidiidae). The genome sequence is 197.0 megabases in span.
John Bishop, Christine Wood
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Sea squirts and immune tolerance [PDF]
Disease Models & Mechanisms, 2009 Transplantation specificity and protective immunity occur in both adaptive and innate branches of the vertebrate immune system. Understanding the mechanisms that underlie specificity and self-tolerance of immune function has major significance, from preventing a rejection reaction after transplantation to dissecting the causes of autoimmune disease ...
Anthony W. De Tomaso
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Introgression between highly divergent sea squirt genomes: an adaptive breakthrough? [PDF]
Peer Community Journal, 2022 Human-mediated introductions are reshuffling species distribution on a global scale. Consequently, an increasing number of allopatric taxa are now brought into contact, promoting introgressive hybridization between incompletely isolated species and new ...
Fraïsse, Christelle +7 more
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