Results 101 to 110 of about 22,375 (299)
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
A TRUE âCANDIDATE IG KAPPA GENEâ IN THE SEA-STAR: <i>ASTERIAS RUBENS</i> (ECHINODERMA) [PDF]
Leclerc
openalex +1 more source
(Uploaded by Plazi from the Biodiversity Heritage Library) No abstract provided.
openaire +1 more source
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Pedicellariae of the crown-of-thorns sea star Acanthaster planci are not an effective defence against fouling [PDF]
Jana Guenther +2 more
openalex +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Molecular mechanisms of tubulogenesis revealed in the sea star hydro-vascular organ. [PDF]
Perillo M +3 more
europepmc +1 more source
Microbial respiration in the asteroid diffusive boundary layer influenced sea star wasting disease during the 2013-2014 northeast Pacific Ocean mass mortality event [PDF]
Ian Hewson
openalex +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source

