Results 141 to 150 of about 22,102 (258)

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Draft genome sequence of <i>Vibrio pectenicida</i> strain FHCF-3, a causative agent of sea star wasting disease in the sunflower sea star (<i>Pycnopodia helianthoides</i>), reveals the genetic potential to produce aerolysin-like toxins. [PDF]

Microbiol Resour Announc
Zhong KX, Chan AM, Prentice MB, Gouin Y, Harvell D, Gehman A-LM, Suttle CA.   +6 more
europepmc   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Manganese Uptake and Lethality in the Sea Star Asterias rubens: Effect of Hypoxia. [PDF]

Bull Environ Contam Toxicol
Bjerregaard P, Hansen SN.
europepmc   +1 more source

Role of Sea Star Platelets, of Sea Star Lymphocytes in Invertebrates

Acta Scientific Pharmaceutical Sciences, 2019
openaire   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Analytical and machine learning approaches identify a sea star steroid with promising activity for COVID-19 therapeutic development. [PDF]

Sci Rep
Abd El Hafez MSM, Maiyza AI, Hassan HA, Osama S, Seadawy MG, El Demellawy MA, Ghareeb DA.   +6 more
europepmc   +1 more source

The Sea With Stars To Sail Her By

, 2020
This music score was submitted for the Kaleidoscope 2020 Call for Scores, an open access collaboration with the UCLA Music Library.
openaire   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Sunflower sea star chemical cues locally reduce kelp consumption by eliciting a flee response in red sea urchins. [PDF]

Proc Biol Sci
Mancuso RT, Gravem SA, Campbell RS, Hunter N, Raimondi P, Galloway AWE, Kroeker KJ.   +6 more
europepmc   +1 more source