Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Star Power: Early life stages of an endangered sea star are robust to current and near-future warming. [PDF]
Hodin J +9 more
europepmc +1 more source
The Sea With Stars To Sail Her By
This music score was submitted for the Kaleidoscope 2020 Call for Scores, an open access collaboration with the UCLA Music Library.
openaire +1 more source
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Draft genome sequence of <i>Vibrio pectenicida</i> strain FHCF-3, a causative agent of sea star wasting disease in the sunflower sea star (<i>Pycnopodia helianthoides</i>), reveals the genetic potential to produce aerolysin-like toxins. [PDF]
Zhong KX +6 more
europepmc +1 more source
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Manganese Uptake and Lethality in the Sea Star Asterias rubens: Effect of Hypoxia. [PDF]
Bjerregaard P, Hansen SN.
europepmc +1 more source
Role of Sea Star Platelets, of Sea Star Lymphocytes in Invertebrates
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Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Analytical and machine learning approaches identify a sea star steroid with promising activity for COVID-19 therapeutic development. [PDF]
Abd El Hafez MSM +6 more
europepmc +1 more source

