Results 191 to 200 of about 15,283,247 (324)

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

An observational case study for inorganic nitrogen dry deposition potential on sea-surface primary production in the subtropical, western North Pacific. [PDF]

Sci Rep
Taketani F, Matsumoto K, Sekiya T, Yamaji K, Kanaya Y.   +4 more
europepmc   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source

Multiscale neural assimilation scheme for high-resolution sea surface temperature reconstruction from satellite observations. [PDF]

Sci Rep
Beauchamp M, Karagali I, Gacitúa G, Høyer JL, Ballarotta M, Fablet R.   +5 more
europepmc   +1 more source

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

FEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang, Mingqiang Deng, Dongmei He, Diqin Lai, Dongjun Liu, Dengyong Zhu, Zhenhua Zhang, Peng Tang, Chuanman Zhou, Menghui Yin, Xichen Bao   +10 more
wiley   +1 more source

CMIP6 models cannot capture long-term forced changes in the tropical Pacific sea surface temperature gradient. [PDF]

Nat Commun
Byrne H, Seager R, Smerdon JE.
europepmc   +1 more source

Robust comparison of climate models with observations using blended land air and ocean sea surface temperatures

, 2015
K. Cowtan, Z. Hausfather, E. Hawkins, P. Jacobs, Michael E. Mann, Sonya K. Miller, B. Steinman, Martin B. Stolpe, R. Way   +8 more
semanticscholar   +1 more source

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

FEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo, Kátia Cristiane Hall, Matheus dos Santos Fernandez, Geovanna Peter Corrêa, Rafael Guerra Lund   +4 more
wiley   +1 more source

Record sea surface temperature jump in 2023-2024 unlikely but not unexpected. [PDF]

Nature
Terhaar J, Burger FA, Vogt L, Frölicher TL, Stocker TF.   +4 more
europepmc   +1 more source