Results 31 to 40 of about 65,852 (261)

Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells

FEBS Open Bio, EarlyView.
To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai, Yong Xu, Jingjing Ma, Ratchanee Duangrat, Chen Yan, Jingyan Liang, Hua Wei, Bin Jiang, Tao‐Sheng Li   +8 more
wiley   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

$$\widehat{P}\widehat{{T}}$$ P ̂ T ̂ symmetry controlled magnetic order switching

npj Computational Materials
Precise electric control of magnetic order and anomalous Hall conductivity (AHC) is pivotal for spintronics. While electric-field control of magnetic order and AHC has been explored in magneto-electric materials, achieving precise and energy-efficient ...
Ziyu Niu, Jing Sun, Zekun Zhang, Xiaohong Zheng, Xixiang Jing, Jingjing Wan, Jing Wang, Junqin Shi, Li-min Liu, Weimin Liu, Xiaoli Fan, Tengfei Cao   +11 more
doaj   +1 more source

Antibacterial activity of silver nanoparticles immobilized in zinc oxide-eugenol cement against Enterococcus Faecalis: an in vitro study

Revista Facultad de Odontología Universidad de Antioquia, 2019
Introduction: the aim of this study is to evaluate the antimicrobial capacity of silver nanoparticles immobilized in a zinc oxide-eugenol (ZOE) cement against Enterococcus faecalis for potential use in endodontic treatments. Method: experimental in vitro
Juan Camilo Duque-Aristizábal, Liza María Isaza-Areiza, Diego Tobón-Calle, Martha Elena Londoño-López   +3 more
doaj   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Investigation of the Mechanical and Thermal Properties of MWCNT/SiC-Filled Ethylene–Butene–Terpolymer Rubber

Crystals
Rubber is widely used in daily lives, such as in automobile tires, conveyor belts, sealing rings, and gaskets. The performance of rubber determines its service life. Therefore, it is of crucial importance to improve the performance of rubber. Theoretical
Li Zhang, Jianming Liu, Duanjiao Li, Wenxing Sun, Zhi Li, Yongchao Liang, Qiang Fu, Nian Tang, Bo Zhang, Fei Huang, Xuelian Fan, Pengxiang Bai, Yuqi Wang, Zuohui Liu, Simin Zhu, Dan Qiao   +15 more
doaj   +1 more source

SRX–Secure Data Backup and Recovery for SGX Applications

IEEE Access, 2022
Intel SGX improves the security of applications by shielding code and data from untrusted software in enclaves. Since enclaves lose their state when closed, that state has to be sealed, i.e., cryptographically protected with a secret key, and stored ...
Daniel Andrade, Joao Silva, Miguel Correia   +2 more
doaj   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

Enhancement of Ethylene-Butene Terpolymer Performance via Carbon Nanotube-Induced Nanodispersion of Montmorillonite Layers

Crystals
In this study, the enhancement mechanism of the nano-dispersion of stearic acid-modified montmorillonite (SMMT) induced by carbon nanotubes (CNTs) in ethylene-butene terpolymer (EBT) was comprehensively investigated, and the regulation effect of ...
Li Zhang, Jianming Liu, Duanjiao Li, Wenxing Sun, Zhi Li, Yongchao Liang, Qiang Fu, Nian Tang, Bo Zhang, Fei Huang, Xuelian Fan, Yuansi Wei, Pengxiang Bai, Yuqi Wang   +13 more
doaj   +1 more source

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

FEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito, Haduki Asano, Ayano Ueki, Joe Sakamoto, Yasuhiro Kamei, Hayato Tokumoto, Ayaka Yazawa, Shigeki Kamitani   +7 more
wiley   +1 more source