Results 41 to 50 of about 1,535 (289)

Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells

FEBS Open Bio, EarlyView.
To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai, Yong Xu, Jingjing Ma, Ratchanee Duangrat, Chen Yan, Jingyan Liang, Hua Wei, Bin Jiang, Tao‐Sheng Li   +8 more
wiley   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

Investigation of aroma carryover risk in a pilot plant and on industrial scale when bottling aromatised and subsequent regular wines on the same filling line

OENO One
Aromatised wine-based beverages and regular wines are commonly bottled on the same bottling line. Sealings installed in the bottling line absorb added aroma compounds from the aromatised wine-based beverages and a subsequent release of the absorbed aroma
Jörg Gottmann, David Müller, Jochen Vestner, Jens Schuster, Ulrich Fischer   +4 more
doaj   +1 more source

The Sacral Knot and Its Iconographic Use [PDF]

Studia Hercynia, 2018
The sacral knot is one of the most discussed symbols of Minoan art. This study focuses on its iconographic use throughout time and tries to find a way to differentiate it from other similar symbols.
Monika Matoušková
doaj  

Sensitivity analysis overlaps of friction elements in cartridge seals

MATEC Web of Conferences, 2018
Cartridge seals are self-contained units consisting of a shaft sleeve, seals, and gland plate. The applications of mechanical seals are numerous. The most common example of application is in bearing production for automobile industry.
Žmindák Milan, Falat Miloš
doaj   +1 more source

Study on the Formation Mechanism of Shale Roof, Floor Sealing, and Shale Self-Sealing: A Case of Member I of the Upper Ordovician Wufeng Formation–Lower Silurian Longmaxi Formation in the Yangtze Region

Frontiers in Earth Science, 2021
Similar to North America, China has abundant shale resources. Significant progress has been made in the exploration and exploitation of shale gas in China since 2009.
Ziya Zhang, Ziya Zhang, Ziya Zhang, Kun Zhang, Kun Zhang, Kun Zhang, Kun Zhang, Yan Song, Yan Song, Zhenxue Jiang, Zhenxue Jiang, Shu Jiang, Shu Jiang, Pengfei Wang, Yong Li, Xiangdong Yin, Xiangdong Yin, Xiangdong Yin, Zhiyuan Chen, Zhengwei Li, Xuejiao Yuan, Xuejiao Yuan, Pei Liu, Pei Liu, Fengli Han, Fengli Han, Liangyi Tang, Liangyi Tang, Yiming Yang, Yiming Yang, Yao Zeng, Yao Zeng   +31 more
doaj   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

Joint sealings of concrete pavements

, 2015
The findings related to issues of joint sealings of concrete pavements are summarized in this bachelor thesis. The main part of this thesis deals with experimental testing of modified asphalt binder. This asphalt binder was tested at the beginning and at
Doseděl, Jan
core   +2 more sources

A Review on the Long-Term Performance of Proton Exchange Membrane Fuel Cells: From Degradation Modeling to the Effects of Bipolar Plates, Sealings, and Contaminants

Energies, 2022
Proton-exchange membrane fuel cells (PEMFCs) are regarded as promising alternatives to internal combustion engines (ICEs) to reduce pollution. Recent research on PEMFCs focuses on achieving higher power densities, reducing the refueling time, mitigating ...
Hossein Pourrahmani, Majid Siavashi, Adel Yavarinasab, Mardit Matian, Nazanin Chitgar, Ligang Wang, Jan Van herle   +6 more
doaj   +1 more source