Results 101 to 110 of about 53,745 (331)

A theoretical analysis of random inspections and fines in invasive species management [PDF]

open access: yes
In this paper, we conduct a theoretical analysis of inspections in a stochastic environment and we shed light on two hitherto unstudied issues concerning inspections in the context of invasive species management.
Seung Jick Yoo, Tao Peng
core  

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

open access: yesMolecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia   +9 more
wiley   +1 more source

The concept of seaports competitiveness measurement

open access: yesContemporary Economy, 2010
Competitiveness research has become an important tool in the politics of the seaport authorities and specific port operators. Measuring the position and competing ability is important and the first step to determine the strengths and weaknesses of a ...
Janusz Dąbrowski
doaj  

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

A theory on the co-evolution of seaports with application to container terminal development in the Rhine-Scheldt Delta [PDF]

open access: yes
How do seaports evolve in relation to each other? Recent studies in port economics and transport geography focused on how supply chain integration has structurally changed the competitive landscape in which individual ports and port actors operate.
Theo Notteboom, Wouter Jacobs
core  

Menorah Review (No. 8, Fall, 1986) [PDF]

open access: yes, 1986
History and Moral Judgment -- Jews in Old China: Some New Findings -- What May We Ask of Holocaust Reflections?

core   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

Ships leaving a port under emergency conditions

open access: yesTransport, 2012
Emergency conditions in a port request special precaution measures taken by ships when in the majority of cases they necessitate leaving port waters in the shortest time.
Vytautas Paulauskas   +3 more
doaj   +1 more source

Administrative and economic dimensions of regionalization: case of Leningrad Province and North-Western Federal District of Russia [PDF]

open access: yes
The North-Western Federal District (NWFD) was created in 2000 within the framework of administrative and territorial division reforming. NWFD appeared together with 6 other districts: Central, Privolzhski, Southern, Urals?, Siberian and Far Eastern.
Felix Fedorovich Rybakov   +2 more
core  

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