PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart +7 more
wiley +1 more source
Evaluating the Location Efficiency of Arabian and African Seaports Using Data Envelopment Analysis (DEA) [PDF]
In this paper the efficiency and performance is evaluated for 22 seaports in the region of East Africa and the Middle East. The aim of our study is to compare seaports situated on the maritime trade road between the East and the West.
Adli Mustaffa +3 more
core
MiR‐513a promotes human erythroid differentiation by modulating c‐Jun
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim +11 more
wiley +1 more source
Railway station development in post-industrial Rotterdam - path dependency and shifting priorities [PDF]
The combined effects of industrial decline and the development of a service economy currently bring about a change in urban economies. Accessibility, proximity and an attractive urban climate are considered important factors of urban competitiveness ...
Jan Jacob Trip
core
Unit Root Test of Import and Export Seaborne Trade in Nigeria Seaports
Pre-ND Program Basic Sciences, Federal College of Agriculture Ishiagu, Ebonyi State,Nigeria
openalex +1 more source
The Application of Kalman Filtering to Predict Vertical Rail Axis Displacements of the Overhead Crane Being a Component of Seaport Transport Structure [PDF]
Daria Filipiak-Kowszyk +1 more
openalex +1 more source
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
Regional networking as success factor in the transformation processes of maritime industry: Experiences and perspectives from Baltic Sea countries [PDF]
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Prause, Gunnar (Ed.)
core
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani +6 more
wiley +1 more source
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo +7 more
wiley +1 more source

