Results 191 to 200 of about 3,297 (265)

Ultrasound‐Actuated Gene Editing in Human Kidney Organoids

open access: yesAdvanced Science, EarlyView.
Peptide‐stabilized nanoemulsions enable spatially controlled, ultrasound‐triggered delivery of gene‐editing proteins deep within human kidney organoid tissues. Focused acoustic pulses drive droplet vaporization, propelling cargo into target renal cells while preserving native tissue microarchitecture. This non‐viral platform improves both the depth and
Michael A. Miller   +6 more
wiley   +1 more source

Single‐Cell Dissection of Therapy‐Induced Remodeling Uncovers a Fibroblast‐Driven Immunosuppressive Niche and Targetable Vulnerabilities in Lethal Prostate Cancer

open access: yesAdvanced Science, EarlyView.
Single‐cell longitudinal profiling reveals that androgen‐deprivation therapy induces a DPT+ fibroblast‐complement axis that suppresses macrophage inflammation and drives CD8+ T cell exhaustion in prostate cancer. Concurrently, resistant epithelial subpopulations persist and engage TSPAN1‐ and NRXN1‐mediated programs promoting CRPC and neuroendocrine ...
Yang Chen   +19 more
wiley   +1 more source

Comparison of Aedes aegypti arbovirus transmission thresholds in two communities with differing water supply infrastructure. [PDF]

open access: yesBMC Public Health
Romero-Vivas CM   +4 more
europepmc   +1 more source

Participatory epidemiological approaches for risk assessment of bed bug (Insecta: Hemiptera: Cimicidae) infestation in public hospitals in the city of Faisalabad, Punjab, Pakistan. [PDF]

open access: yesBMC Public Health
Ashraf A   +10 more
europepmc   +1 more source

One response: Global Outbreak Alert and Response Network supporting the COVID-19 response, Kiribati. [PDF]

open access: yesWestern Pac Surveill Response J
Laurie L   +6 more
europepmc   +1 more source

Characterizing Patient Diversity via Healthcare Access Determinants: A New Approach for Measuring Improvements in Clinical Trial Diversity in the United States. [PDF]

open access: yesAdv Ther
Yu J   +9 more
europepmc   +1 more source

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