Results 81 to 90 of about 53,745 (331)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
The Beginnings of a Small Ethiopian, Organizational Leadership Library Collaborative
, 2007 An Azusa Pacific University Reference Librarian describes the logistical, cultural, and spiritual aspects of a library building journey to Ethiopia which brought the means for a successful implementation of a new small academic library to hundreds of ...
Shimazu Yee, Evelyn
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Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Smart Technologies for Environmental Safety and Knowledge Enhancement in Intermodal Transport [PDF]
International concerns about security in transport systems are leading to a new international regulation in this field. This introduces new requirements for operators and authorities as well as it opens new challenges, in particular when referred to ...
Dino Borri +3 more
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Compensatory Measures in European Nature conservation law [PDF]
, 2014 The Birds and Habitats Directives are the cornerstones of EU nature conservation law, aiming at the conservation of the Natura 2000 network, a network of protected sites under these directives, and the protection of species.
Van Hoorick, Geert
core +3 more sources
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Located in Mystic, Connecticut, Mystic Seaport, The Museum of America and the Sea, is the nation's leading maritime museum. Site features a wealth of information for your visit.
core +1 more source
An analysis of the treatment of New England in eight fifth grade geography textbooks [PDF]
, 1951 Thesis (Ed.M.)--Boston ...
Green, Mary Louise
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E-commerce, Warehousing and Distribution Facilities in California: A Dynamic Landscape and the Impacts on Disadvantaged Communities [PDF]
, 2020 This work addresses the distribution of warehouses and distribution centers (W&DCs) influenced by e-commerce, through spatial analysis and econometric modelling.
Jaller, Miguell, PhD +2 more
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