Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective In multiple sclerosis, the optimal time for deploying a therapeutic intervention is before the central nervous system is damaged; given the success of trials treating the earliest stage of MS, the radiologically isolated syndrome, developing primary prevention strategies is an important next challenge.
Amy W. Laitinen +7 more
wiley +1 more source
Transitioning towards hydrogen powered seaport yard cranes for low carbon transformation based on a multiple factor real option model. [PDF]
Sci RepYang A, Zhang Y, He R, Wang Q, Gao J.
europepmc +1 more source
No country is safe from a pandemic: insights into small countries' COVID-19 experiences. [PDF]
Eur J Public Health, 2023 Cuschieri S, Bejko D, Stranges S.
europepmc +1 more source
Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina +11 more
wiley +1 more source
[Pathogen Surveillance in Wastewater from Airport and Port in the Chungcheong Region, Republic of Korea, in 2024]. [PDF]
Jugan Geongang Gwa JilbyeongYoon Y, Kim S, Lee DG, Kim BR, Jeon JH.
europepmc +1 more source
Annals of Clinical and Translational Neurology, EarlyView.Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao +6 more
wiley +1 more source
An Event-Link Network Model Based on Representation in P-Space. [PDF]
Entropy (Basel)Zhang W, Chen X, Deng W.
europepmc +1 more source
An Evaluation of the Need and Cost of Selected Trade Facilitation Measures in Bangladesh: Implications for the WTO Negotiations on Trade Facilitation [PDF]
With the ongoing customs reforms in Bangladesh, the possible future negotiations on trade facilitation in the WTO will have a profound impact on Bangladesh, as well as on other LDC and developing countries.
Debapriya Bhattacharya +1 more
core
SPG4 and Dementia: Expanding the Clinical Spectrum
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza +19 more
wiley +1 more source
Invasive mosquito surveillance in the United Kingdom 2020 to 2024: First detection of Aedes aegypti eggs in the UK and further detection of Aedes albopictus. [PDF]
PLOS Glob Public HealthJohnston CJ +23 more
europepmc +1 more source