Results 81 to 90 of about 2,047,738 (269)
Scientific ReportsBased on a review of the fundamental principles of the Newmark sliding displacement method, this paper proposes an improved approach based on the upper bound solution of plastic mechanics, drawing on the theory of Academician Zuyu Chen, which states that
Pengxu Jing +9 more
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Joint Representation Learning for Retrieval and Annotation of Genomic Interval Sets
BioengineeringAs available genomic interval data increase in scale, we require fast systems to search them. A common approach is simple string matching to compare a search term to metadata, but this is limited by incomplete or inaccurate annotations. An alternative is
Erfaneh Gharavi +5 more
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Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Current Biology, 2000 Abstract Visual search is the process of finding things that you are looking for in a world full of things that you are not looking for. Search tasks are ubiquitous. Many are so routine that we do not think of them as search tasks (e.g., Where is the space bar on the keyboard?). Others are more taxing (Where is the cat hiding?) and/or
openaire +2 more sources
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
PubMed Search: How to get Optimum Results?
Delhi Journal of Ophthalmology, 2019 There are many articles published regularly in the literature dealing with various aspects of “Research Methodology”. Techniques of manuscript writing and various strategies for statistical analysis have been very well documented in the past.
Ashish Mahobia +2 more
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Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Journal of Combinatorial Theory, Series A, 1996 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
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Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source