Results 111 to 120 of about 4,883,203 (354)

BigDataBench: a Big Data Benchmark Suite from Internet Services

open access: yes, 2014
As architecture, systems, and data management communities pay greater attention to innovative big data systems and architectures, the pressure of benchmarking and evaluating these systems rises.
Gao, Wanling   +14 more
core   +1 more source

Thermal proteome profiling and proteome analysis using high‐definition mass spectrometry demonstrate modulation of cholesterol biosynthesis by next‐generation galeterone analog VNPP433‐3β in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan   +10 more
wiley   +1 more source

Gunrock: GPU Graph Analytics

open access: yes, 2017
For large-scale graph analytics on the GPU, the irregularity of data access and control flow, and the complexity of programming GPUs, have presented two significant challenges to developing a programmable high-performance graph library.
Davidson, Andrew   +10 more
core   +2 more sources

Elucidating prognostic significance of purine metabolism in colorectal cancer through integrating data from transcriptomic, immunohistochemical, and single‐cell RNA sequencing analysis

open access: yesMolecular Oncology, EarlyView.
Low expression of five purine metabolism‐related genes (ADSL, APRT, ADCY3, NME3, NME6) was correlated with poor survival in colorectal cancer. Immunohistochemistry analysis showed that low NME3 (early stage) and low ADSL/NME6 (late stage) levels were associated with high risk.
Sungyeon Kim   +8 more
wiley   +1 more source

Knowing How Good Our Searches Are: An Approach Derived from Search Filter Development Methodology

open access: yesEvidence Based Library and Information Practice, 2015
Objective – Effective literature searching is of paramount importance in supporting evidence based practice, research, and policy. Missed references can have adverse effects on outcomes.
Sarah Lindsay Hayman
doaj   +3 more sources

An Integrated Data Analytics Platform

open access: yesFrontiers in Marine Science, 2019
An Integrated Science Data Analytics Platform is an environment that enables the confluence of resources for scientific investigation. It harmonizes data, tools and computational resources to enable the research community to focus on the investigation ...
Edward M. Armstrong   +18 more
doaj   +1 more source

Looking at a digital research data archive - Visual interfaces to EASY

open access: yes, 2012
In this paper we explore visually the structure of the collection of a digital research data archive in terms of metadata for deposited datasets. We look into the distribution of datasets over different scientific fields; the role of main depositors ...
Bosch, Olav ten   +2 more
core   +1 more source

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

open access: yesMolecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser   +11 more
wiley   +1 more source

APIs and Your Privacy [PDF]

open access: yes, 2019
Application programming interfaces, or APIs, have been the topic of much recent discussion. Newsworthy events, including those involving Facebook’s API and Cambridge Analytica obtaining information about millions of Facebook users, have highlighted the ...
Russell, N. Cameron
core   +1 more source

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