Results 121 to 130 of about 275,444 (319)

Unveiling unique protein and phosphorylation signatures in lung adenocarcinomas with and without ALK, EGFR, and KRAS genetic alterations

open access: yesMolecular Oncology, EarlyView.
Proteomic and phosphoproteomic analyses were performed on lung adenocarcinoma (LUAD) tumors with EGFR, KRAS, or EML4–ALK alterations and wild‐type cases. Distinct protein expression and phosphorylation patterns were identified, especially in EGFR‐mutated tumors. Key altered pathways included vesicle transport and RNA splicing.
Fanni Bugyi   +12 more
wiley   +1 more source

Discovering Digital Library User Behavior with Google Analytics

open access: yesCode4Lib Journal, 2012
Google Analytics has advanced features for tracking search queries, events such as clicking external links or downloading files, which you can use to track user behavior that is normally difficult to track with traditional web logging software.
Kirk Hess
doaj  

Data Analytics, Decision-Making Process and Business Performance: A Bibliometric Analysis

open access: yesStudies in Business and Economics
Considering the growing demand for data analytics and the increasing development data analytical tools, the present study aims to provide a summative state-of-the-art of the available literature on the impact of data analytics on decision-making and ...
Radu Alexandra, Herciu Mihaela
doaj   +1 more source

IMPLEMENTASI TEKNIK SEARCH ENGINE OPTIMIZATION (SEO) MENGGUNAKAN METODE WHITE HAT SEO PADA WEBSITE XUZU (STUDI KASUS: PT. BINTANG KONVEKSI INDO) [PDF]

open access: yes
PT Bintang Konveksi Indo is a clothing and accessories manufacturing company, including PDH shirts, organization shirts, and graduation kits. The company also introduced the XUZU brand with a focus on quality, design, and excellent service.
Cahyanto, Mochammad Andre
core  

Targeting of PTP4A3 overexpression sensitises HGSOC cells towards chemotherapeutic drugs

open access: yesMolecular Oncology, EarlyView.
In HGSOC with normal KRAS expression, high PTP4A3 expression regulates autophagy activation. Conversely, in HGSOC with high KRAS expression, KRAS dictates autophagy control, and PTP4A3 is not required. When high PTP4A3 expression is inhibited, HGSOC cells are preferentially sensitised towards DNA‐damaging agents.
Ana López‐Garza   +3 more
wiley   +1 more source

Olaparib synergy screen reveals Exemestane induces replication stress in triple‐negative breast cancer

open access: yesMolecular Oncology, EarlyView.
Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh   +5 more
wiley   +1 more source

Beyond the List: A Framework for the Design of Next-Generation MEDLINE Search Tools

open access: yesData
Despite the critical importance of biomedical databases like MEDLINE, users are often hampered by search tools with stagnant designs that fail to support complex exploratory tasks. To address this limitation, we synthesized research from visual analytics
Vladimir Zhurov   +2 more
doaj   +1 more source

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