Results 131 to 140 of about 275,444 (319)

DeepLife: An Entity-aware Search, Analytics and Exploration Platform for Health and Life Sciences [PDF]

, 2016
Patrick Erñst, Amy Siu, Dragan Milchevski, Johannes Hoffart, Gerhard Weikum   +4 more
openalex   +1 more source

DISCREPANCY PARAMETERS OF APPROXIMATIONS OF DISCRETELY SPECIFIED DEPENDENCIES BY ANALYTICAL FUNCTIONS AND SEARCH CRITERIA FOR OPTIMAL VALUES OF THEIR COEFFICIENTS

, 2021
Svetlana Zakharchenko, N.A. Shydlovska, Iryna Mazurenko   +2 more
openalex   +2 more sources

RKIP overexpression reduces lung adenocarcinoma aggressiveness and sensitizes cells to EGFR‐targeted therapies

Molecular Oncology, EarlyView.
RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha, Joana Pinheiro, Rui F. Marques, Patrícia Fontão, Diana Cardoso‐Carneiro, Adriana Mendes, Izabela N. F. Gomes, Ana Carolina Laus, Renato J. da Silva‐Oliveira, Rui Manuel Reis, Olga Martinho   +10 more
wiley   +1 more source

Leveraging Learning Analytics to Improve the User Experience of Learning Management Systems in Higher Education Institutions

Information
This systematic review examines the application of learning analytics to enhance user experience within Learning Management Systems in higher education institutions.
Patrick Ngulube, Mthokozisi Masumbika Ncube   +1 more
doaj   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source

The Search for a Generalized Analytical Solution for the Inverse Problem; Some Surprisingly Simple Approximate Methods for Problems of Practical Importance

, 2023
A. E. Segall
openalex   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

Molecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian, Sriraam Sivachandran, Melissa Galati, Brandon Ramchatesingh, Hibo Rijal, Johnny Hanna, Elena Netchiporouk, May Chergui, Margaret Redpath, Samy Abou Setah, Ivan V. Litvinov   +10 more
wiley   +1 more source

Should competing sellers adopt the data analytics service to enable product improvement in online marketplace

Journal of Management Science and Engineering
More and more marketplace platforms choose to use the data gathered from consumers (e.g., customer search terms, demographics) to provide a data analytics service for third-party sellers, both encouraging innovations and improving the operations of the ...
Danyu Liang, Minqiang Li, Haiyang Feng, Nan Feng   +3 more
doaj   +1 more source

Speculative Approximations for Terascale Analytics

, 2014
Model calibration is a major challenge faced by the plethora of statistical analytics packages that are increasingly used in Big Data applications. Identifying the optimal model parameters is a time-consuming process that has to be executed from scratch ...
Qin, Chengjie, Rusu, Florin
core