Whole‐Blood RNA Sequencing Profiling of Patients With Rheumatoid Arthritis Treated With Tofacitinib
Objective Patients with rheumatoid arthritis (RA) often fail to respond to therapies, including JAK inhibitors (JAKi), and treatment allocation is made via a trial‐and‐error strategy. A comprehensive analysis of responses to JAKi, including tofacitinib, by RNA sequencing (RNAseq) would allow the discovery of transcriptomic markers with a two‐fold ...
Chiara Bellocchi+11 more
wiley +1 more source
PanKB: An interactive microbial pangenome knowledgebase for research, biotechnological innovation, and knowledge mining. [PDF]
Sun B+8 more
europepmc +1 more source
AI optimization algorithms enhance higher education management and personalized teaching through empirical analysis. [PDF]
Xu X.
europepmc +1 more source
Harnessing artificial intelligence for infection control and prevention in hospitals: A comprehensive review of current applications, challenges, and future directions. [PDF]
Alhusain FA.
europepmc +1 more source
The cost as a function of the number of experiments for a non‐symmetric 21×21$$ 21\times 21 $$ system. Four approaches are shown: the proposed stochastic conjugate gradient ILC (SCGILC) method (), deterministic conjugate gradient ILC (), stochastic gradient descent ILC () and deterministic gradient descent ILC ().
Leontine Aarnoudse, Tom Oomen
wiley +1 more source
Electronic Health Records: A Gateway to AI-Driven Multimorbidity Solutions-A Comprehensive Systematic Review. [PDF]
Ioakeim-Skoufa I+13 more
europepmc +1 more source
Performance Triggered Adaptive Model Reduction for Soil Moisture Estimation in Precision Irrigation
ABSTRACT Accurate soil moisture information is essential for precise irrigation to enhance water use efficiency. Estimating soil moisture based on limited soil moisture sensors is especially critical for obtaining comprehensive soil moisture information when dealing with large‐scale agricultural fields.
Sarupa Debnath+4 more
wiley +1 more source
Synthesizing Public Health Preparedness Mechanisms for High-Impact Infectious Disease Threats: A Jurisdictional Scan. [PDF]
Saif-Ur-Rahman KM+9 more
europepmc +1 more source
Chromatin, which organizes DNA, changes its structure to adapt to stress like high oxygen levels (hyperoxia), which can damage cells. Researchers developed a technique to observe these changes and found variability in how different parts of chromatin remodel.
Lauren Monroe+4 more
wiley +1 more source
Secondary use of health records for prediction, detection, and treatment planning in the clinical decision support system: a systematic review. [PDF]
Pant D+10 more
europepmc +1 more source