Results 101 to 110 of about 136,944,853 (238)

Time perspective as predictor of meaning in life [PDF]

, 2014
The purpose of this study was to determine whether meaning in life among Macedonian students can be predicted based on their dominant orientation toward past, present or future. Participants in the study were 252 students aged 18 to 27 years.
Achkovska-Leshkovska, Elena, Shterjovska, Marija, Achkovska Leshkovska, Elena   +2 more
core   +1 more source

Ability to mentalize and the sense of meaning in life in the professional group of nurses: a cross-sectional study

Medycyna Pracy
Background Mentalization supports emotion regulation and interpersonal functioning, and meaning in life is a key psychological resource in nursing. This study examined associations between mentalizing capacity and meaning in life among practicing nurses.
Łukasz Krzewiński, Patrycja Basińska
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Mental health and meaning in life in Chinese military personnel: a cross-lagged analysis

BMC Psychology
Background The burgeoning field of research on the dual-factor model of mental health (DFM) has highlighted its significance, yet the applicability of the DFM in military personnel and its longitudinal relationships with different dimensions of meaning ...
Bin Liu, Mingxuan Zou, Hongxiang Bao, Xiang Xu, Xiaohui Liu, Bing Zhang, Qun Yang, Fengzhan Li   +7 more
doaj   +1 more source

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

Molecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic, Maria Concetta Vitale, Rita Siino, Emilia Di Giovanni, Carla Ferrante Bannera, Enrico Di Marco, Andrea Gottardo, Tancredi Didier Bazan Russo, Nadia Barraco, Alessandro Perez, Valerio Gristina, Antonio Galvano, Giuseppe Badalamenti, Antonio Russo, Viviana Bazan, Lorena Incorvaia   +15 more
wiley   +1 more source

The relationship between problematic mobile phone use and meaning in life among adolescents: a latent profile analyses

BMC Psychology
Purpose This study utilized Latent Profile Analysis to identify distinct profiles of meaning in life (MiL) among adolescents. Additionally, it aimed to investigate the relationships and specific impacts of sociodemographic variables and problematic ...
Naiyang Peng, Qilong Sun, Zuxian Li, Xue Xia, Yansong Li   +4 more
doaj   +1 more source

The relationship of acculturative stress with meaning in life through the mediating role of difficulties in emotion regulation and meaning-centered coping style among international students in Germany

Frontiers in Psychology
IntroductionWith the increasing trend of international academic mobility, understanding the psychological outcomes of cultural transition has become crucial.
Rasa Soufi Amlashi, Simon Forstmeier
doaj   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

Personality and purpose of life: the moderating role of existential emptiness in the link of ontological perception of time and search for meaning in life

In this paper, we analyzed the relationship between personality traits and some existential variables (meaning in life, search for meaning, and ontological perception of time).
Loureto, Gleidson Diego Lopes, Alves, Guylherme Barbosa Siqueira, Silva, W. A. D.   +2 more
core   +1 more source