Results 181 to 190 of about 2,544,042 (295)

Appraisal of Gene Expression‐Based Classifiers for Neuropsychiatric Disorders: A Meta‐Regression

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, Volume 201, Issue 2, Page 93-104, March 2026.
ABSTRACT A substantial body of research examines the potential of gene‐expression‐based biomarkers for diagnosing and selecting treatments for neuropsychiatric disorders, yet no clear consensus has been reached regarding the influence of controllable factors such as study design and model selection on the performance of gene‐expression‐based ...
Ali Razavi, Brittany Arensman, Eric J. Barnett, Leo A. Lee, Stephen V. Faraone, Stephen J. Glatt, Jonathan L. Hess   +6 more
wiley   +1 more source

Improving event-based methods for modelling flood risk in a variable and non-stationary climate. [PDF]

Philos Trans A Math Phys Eng Sci
Nathan R.
europepmc   +1 more source

Coherent Disaggregation and Uncertainty Quantification for Spatially Misaligned Data

Environmetrics, Volume 37, Issue 2, March 2026.
ABSTRACT Spatial misalignment arises when datasets are aggregated or collected at different spatial scales, leading to information loss. We develop a Bayesian disaggregation framework that links misaligned data to a continuous‐domain model through an iteratively linearised integration scheme implemented with the Integrated Nested Laplace Approximation (
Man Ho Suen, Mark Naylor, Finn Lindgren
wiley   +1 more source

Dynamic infrared thermography in free flap surgery: A systematic review. [PDF]

JPRAS Open
Clarys W, Hotome V, Hummelink S, Verspeek S, Verhoeven V, Tjalma WAA, Steenackers G, Thiessen F.   +7 more
europepmc   +1 more source

Parametric Design: A Search for Membrane Structures

, 2012
This report deals with shape optimization. Curved beams and thin shells are optimized with respect to internal bending moments. The shape optimization focuses solely on the shape of centroidal axes and middle surfaces, i.e. cross sections and shell thicknesses remain constant. The main part of the report is a presentation of three different cases, each
openaire   +1 more source

Iterative Mold Adaptation for Pre‐Compensation of Warpage in Aluminum Casting

PAMM, Volume 26, Issue 1, March 2026.
ABSTRACT As a result of uneven cooling and internal stresses, warpage is a significant challenge in metal casting, particularly when using metal dies. Previous research has sought to reduce warpage by adjusting process parameters, such as the extraction temperature.
Steffen Tillmann, Shrujal Gor, Stefanie Elgeti, Andreas Bührig‐Polaczek, Björn Pustal   +4 more
wiley   +1 more source

Integrated <i>In Vitro</i>/<i>In Silico</i> Uncertainty Quantification Method for Protein Crystallization Models. [PDF]

Ind Eng Chem Res
Pessina D, Calderon De Anda J, Heffernan C, Heng JYY, Papathanasiou MM.   +4 more
europepmc   +1 more source

In Silico Structural Analysis of Human β‐Glucuronidase for Antibody–Drug Conjugates Optimization

Proteins: Structure, Function, and Bioinformatics, Volume 94, Issue 3, Page 838-852, March 2026.
ABSTRACT Human β‐glucuronidase (HGUSB), a key lysosomal glycosyl hydrolase for the degradation pathway of glycosaminoglycans (GAGs), plays a crucial role in cell proliferation and inflammation, making it a promising target for novel therapeutic strategies including antibody‐drug conjugates (ADCs) with β‐glucuronic linkers.
Giorgia Canini, Simona Saporiti, Crescenzo Coppa, Mara Rossi, Fabio Centola, Alessandro Arcovito   +5 more
wiley   +1 more source

Parametrization of Zirconium for DFTB3/3OB: A Pathway to Study Complex Zr-Compounds for Biomedical and Material Science Applications. [PDF]

J Comput Chem
Penz A, Gamper J, Gallmetzer JM, Purtscher FRS, Hofer TS.   +4 more
europepmc   +1 more source

Parametric search made practical*1

Computational Geometry, 2004
openaire   +1 more source