Results 91 to 100 of about 2,429,355 (361)

Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells

Molecular Oncology, EarlyView.
In the era of immunotherapies, many patients either do not respond or eventually develop resistance. We propose to pave the way for proteomic analysis of surface‐expressed proteins called surfaceome, of circulating tumor cells. This approach seeks to identify immune evasion mechanisms and discover potential therapeutic targets. Circulating tumor cells (
Doryan Masmoudi, Jérome Vialaret, Christophe Hirtz, Catherine Alix‐Panabières   +3 more
wiley   +1 more source

Multi-User Searchable Symmetric Encryption with Dynamic Updates for Cloud Computing

Information, 2018
With the advent of cloud computing, more and more users begin to outsource encrypted files to cloud servers to provide convenient access and obtain security guarantees.
Chen Guo, Xingbing Fu, Yaojun Mao, Guohua Wu, Fagen Li, Ting Wu   +5 more
doaj   +1 more source

Semantic, Efficient, and Secure Search over Encrypted Cloud Data [PDF]

arXiv, 2020
Companies and individuals demand more and more storage space and computing power. For this purpose, several new technologies have been designed and implemented, such as the cloud computing. This technology provides its users with storage space and computing power according to their needs in a flexible and personalized way.
arxiv  

Clinical significance of stratifying prostate cancer patients through specific circulating genes

Molecular Oncology, EarlyView.
We tested a specific panel of genes representative of luminal, neuroendocrine and stem‐like cells in the blood of prostate cancer patients, showing predictive value from diagnosis to late stages of disease. This approach allows monitoring of treatment responses and outcomes at specific time points in trajectories.
Seta Derderian, Edouard Jarry, Arynne Santos, Quentin Vesval, Lucie Hamel, Rafael Sanchez‐Salas, Alexis Rompré‐Brodeur, Wassim Kassouf, Raghu Rajan, Fadi Brimo, Marie Duclos, Armen Aprikian, Simone Chevalier   +12 more
wiley   +1 more source

Privacy-Preserving Multi-Keyword Searchable Encryption for Distributed Systems

IEEE Transactions on Parallel and Distributed Systems, 2021
As cloud storage has been widely adopted in various applications, how to protect data privacy while allowing efficient data search and retrieval in a distributed environment remains a challenging research problem.
Xueqiao Liu, Guomin Yang, W. Susilo, Joseph Tonien, Ximeng Liu, Jian Shen   +5 more
semanticscholar   +1 more source

MET variants with activating N‐lobe mutations identified in hereditary papillary renal cell carcinomas still require ligand stimulation

Molecular Oncology, EarlyView.
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin, Audrey Vinchent, Marie Fernandes, Isabelle Damour, Agathe Laratte, Rémi Tellier, Gabriella O. Estevam, Jean‐Pascal Meneboo, Céline Villenet, Clotilde Descarpentries, James S. Fraser, Martin Figeac, Alexis B. Cortot, Etienne Rouleau, David Tulasne   +14 more
wiley   +1 more source

Plasma lipidomic and metabolomic profiles in high‐grade glioma patients before and after 72‐h presurgery water‐only fasting

Molecular Oncology, EarlyView.
Presurgery 72‐h fasting in GB patients leads to adaptations of plasma lipids and polar metabolites. Fasting reduces lysophosphatidylcholines and increases free fatty acids, shifts triglycerides toward long‐chain TGs and increases branched‐chain amino acids, alpha aminobutyric acid, and uric acid.
Iris Divé, Lisa Hahnefeld, Katharina J. Wenger, Donat Kögel, Joachim Steinbach, Gerd Geisslinger, Michael W. Ronellenfitsch, Irmgard Tegeder   +7 more
wiley   +1 more source

Achieving Secure and Efficient Cloud Search Services: Cross-Lingual Multi-Keyword Rank Search over Encrypted Cloud Data

, 2019
Multi-user multi-keyword ranked search scheme in arbitrary language is a novel multi-keyword rank searchable encryption (MRSE) framework based on Paillier Cryptosystem with Threshold Decryption (PCTD).
Abedin, Zain Ul, Du, Xiaojiang, Guan, Zhitao, Guizani, Mohsen, Liu, Xueyan, Wu, Longfei   +5 more
core   +1 more source

Distributed Searchable Asymmetric Encryption

Indonesian Journal of Electrical Engineering and Computer Science, 2016
<p><em>Searchable asymmetric encryption (SAE) can also be called Public Key Encryption with Keyword Search (PEKS), which allows us to search the keyword on the data of having been encrypted. The essence of Asymmetric searchable encryption is that users exchange the data of encryption, one party sends a ciphertext with key encryption, the ...
Jie Liu, Shoulin Yin, Lin Teng
openaire   +2 more sources

Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM

Molecular Oncology, EarlyView.
CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak, Żaneta Zarębska, Marcin P. Sajek, Adriana Grabowska, Alessia Buratin, Paweł Głodowicz, Julia O. Misiorek, Konrad Kuczyński, Stefania Bortoluzzi, Marek Żywicki, Jan G. Kosiński, Agnieszka Rybak‐Wolf, Rafał Piestrzeniewicz, Anna M. Barciszewska, Katarzyna Rolle   +14 more
wiley   +1 more source