Results 271 to 280 of about 2,429,355 (361)

Wonders of Harbor and Grey Seal Whiskers: Morphology, Natural Frequencies, and 3D Modeling

Advanced Science, EarlyView.
Seals detect prey by sensing vortices using whiskers. How whisker morphologies and locations respond to hydrodynamic signals across various frequencies remains unclear. This study measures whiskers’ natural frequencies and morphologies and maps them to whisker locations on the muzzle, providing insights into how seals interpret hydrodynamic signals ...
Xingwen Zheng, Amar M. Kamat, Ming Cao, Michael S. Triantafyllou, Ajay Giri Prakash Kottapalli   +4 more
wiley   +1 more source

SQUiD: ultra-secure storage and analysis of genetic data for the advancement of precision medicine. [PDF]

Genome Biol
Blindenbach J, Kang J, Hong S, Karam C, Lehner T, Gürsoy G.   +5 more
europepmc   +1 more source

Replicating PET Hydrolytic Activity by Positioning Active Sites with Smaller Synthetic Protein Scaffolds

Advanced Science, EarlyView.
A workflow is proposed for the computational design of new‐to‐nature PET hydrolases by remodeling the protein scaffold. Starting from the functional motifs extracted from a template enzyme, designer enzymes are generated following four steps: scaffold remodeling, computational screening, experimental validation, and sequence refinement.
Yujing Ding, Shanshan Zhang, Xian Kong, Henry Hess, Yifei Zhang   +4 more
wiley   +1 more source

Retrieval Integrity Verification and Multi-System Data Interoperability Mechanism of a Blockchain Oracle for Smart Healthcare with Internet of Things (IoT) Integration. [PDF]

Sensors (Basel)
Zhou Z, Chen L, Zhao Y, Yang X, Han Z, He Z.   +5 more
europepmc   +1 more source

The INAVA mRNA in Extracellular Vesicles Activates Normal Ovarian Fibroblasts by Phosphorylation–Ubiquitylation Crosstalk of HMGA2

Advanced Science, EarlyView.
Ovarian cancer‐derived extracellular vesicles (EVs) transfer INAVA mRNA to normal ovarian fibroblasts (NOFs). Translated INAVA protein inhibits HMGA2 phosphorylation‐dependent ubiquitylation and proteasomal degradation, promoting NOF activation.
Lingkai Gu, Zhangjin Shen, Shizhen Shen, Conghui Wang, Yuwan Liu, Xinyi Wei, Mengxia Zheng, Jiaxin Gu, Xiaojing Chen, Yi Sun, Junfen Xu, Yan Lu, Weiguo Lu   +12 more
wiley   +1 more source

IoT data security in outsourced databases: A survey of verifiable database. [PDF]

Heliyon
Chen A, Yu S, Yang X, Huang D, Ren Y.
europepmc   +1 more source

Facilitating crRNA Design by Integrating DNA Interaction Features of CRISPR‐Cas12a System

Advanced Science, EarlyView.
This study introduces a novel approach combining molecular dynamics simulations and neural network modeling to predict the Cas12a trans‐cleavage activity. By integrating sequence and molecular interaction features, prediction accuracy is enhanced, and identify key features affecting Cas12a trans‐cleavage activity.
Zhihao Yao, Wanglu Li, Kaiyu He, Hongmei Wang, Yan Xu, Qun Wu, Liu Wang, Yao Nie   +7 more
wiley   +1 more source

A secure healthcare data sharing scheme based on two-dimensional chaotic mapping and blockchain. [PDF]

Sci Rep
Xu Z, Zheng E, Han H, Dong X, Dang X, Wang Z.   +5 more
europepmc   +1 more source

Potent Cross‐neutralizing Antibodies Reveal Vulnerabilities of Henipavirus Fusion Glycoprotein

Advanced Science, EarlyView.
Hendra and Nipah viruses (HNVs) pose significant threats to global health. This work reports potent cross‐neutralizing antibodies targeting the fusion glycoprotein (F) and reveals shared features of these antibodies and vulnerabilities of F, thereby guiding the rational design of countermeasures against HNVs and similar pathogens.
Yi Ren, Pengfei Fan, Xinghai Zhang, Ting Fang, Zhengshan Chen, Yanfeng Yao, Xiangyang Chi, Guanying Zhang, Xiaofan Zhao, Bingjie Sun, Fangxu Li, Zixuan Liu, Zhenwei Song, Baoyue Zhang, Cheng Peng, Entao Li, Yilong Yang, Jianmin Li, Sandra Chiu, Changming Yu   +19 more
wiley   +1 more source

Secure and intelligent 5G-enabled remote patient monitoring using ANN and Choquet integral fuzzy VIKOR. [PDF]

Sci Rep
Chinnaperumal S, Periyasamy M, Alhussan AA, Kannan S, Khafaga DS, Raju SK, Eid MM, El-Kenawy EM.   +7 more
europepmc   +1 more source