Results 61 to 70 of about 18,276 (243)

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

A Unique Presentation of Meibomian Gland Carcinoma

Delhi Journal of Ophthalmology, 2021
Background:- The sebaceous gland carcinoma is a lethal highly malignant slow-growing tumor of the eyelid arising from meibomian glands, glands of Zeis, sebaceous glands of caruncle, and periocular skin.
Ashish Kumar Pandey, Anirudh Singh, Mansur Ali Khan, Anjali Maheshwari   +3 more
doaj   +1 more source

Citologia de impressão na avaliação de tumores da superfície ocular: artigo de revisão [PDF]

, 2015
Impression cytology (IC) has been widely used as a method for evaluating the ocular surface and superficial cells layers in the diagnosis and follow-up after treatment of several ocular surface tumors of both epithelial and melanocytic origin ...
Araujo de Almeida, Simone Ribeiro, Barros, Jeison de Nadai, Cunha, Marcelo Carvalho da, Gomes, José Álvaro Pereira, Lowen, Marcia Serva   +4 more
core   +2 more sources

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Clinicopathological Analysis and Surgical Outcome of Eyelid Malignancies: A Study of 332 Cases

Journal of Skin Cancer, 2022
Background. Eyelid tumours are common in our ophthalmic practice. Malignancy cases account only for one-fourth of all eyelid tumours. The most aggressive eyelid malignancy is sebaceous gland carcinoma, but its occurrences are rare in western countries ...
Syeed Mehbub Ul Kadir, Mukti Rani Mitra, Riffat Rashid, Murtuza Nuruddin, Md. Kamrul Hassan Khan, Golam Haider, Mst. Sayedatun Nessa   +6 more
doaj   +1 more source

Malignant appearing benign lid tumor – An isolated upper lid schwannoma

Kerala Journal of Ophthalmology, 2023
Sebaceous carcinoma is notorious for masquerading as other benign and malignant lesions. A 50-year-old male presented with a painless mass on the lateral aspect of the right upper lid. On examination, there was a 25 mm ××× 20 mm ×× 14 mm, nontender, well-
Sahil Agrawal, Manasi Tripathi, Mandeep Singh Bajaj, Deepsekhar Das   +3 more
doaj   +1 more source

Basal cell carcinoma within nevus sebaceous of the trunk [PDF]

Baylor University Medical Center Proceedings, 2019
We report the first case of an 82-year-old woman with five basal cell carcinomas within a large nevus sebaceous of the trunk. Nevus sebaceous of Jadassohn is a congenital cutaneous hamartoma affecting 0.3% of newborns. Clinical diagnosis is based on its distinctive hairless, orange-brown appearance.
Ian T. Watson, Andrew DeCrescenzo, So Yeon Paek   +2 more
openaire   +2 more sources

β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations

Advanced Biology, Volume 9, Issue 3, March 2025.
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio, B. Spedicato, G. Corallo, A. Inguscio, M. Greco, D. Musarò, D. Vergara, A. F. Muro, G. De Sabbata, L. R. Soria, N. Brunetti Pierri, M. Maffia   +11 more
wiley   +1 more source

Trichilemmal carcinoma of the scalp: Demystifying anecdote of a rare entity

Archives of Medicine and Health Sciences, 2021
Trichilemmal carcinoma (TC) is a rare malignant adnexal neoplasm, falling under the umbrella of tumors with follicular differentiation generally presenting as papulonodular growth with surface ulceration over sun-exposed skin.
Archana Shetty, Aparna Muralidhar, Nidha Gaffoor   +2 more
doaj   +1 more source

Ileocecal Adenocarcinoma and Ureteral Transitional Cell Carcinoma with Multiple Sebaceous Tumors and Keratoacanthomas in a Case of Muir-Torre Syndrome

Dermatology Research and Practice, 2010
Cutaneous neoplasms including sebaceous tumors, keratoacanthomas, and basal cell carcinomas with sebaceous differentiation can be markers of internal malignancy associated with the Muir-Torre Syndrome (MTS).
Michael C. Lynch, Bryan E. Anderson
doaj   +1 more source