Results 1 to 10 of about 190,698 (290)
Primary sebocytes and sebaceous gland cell lines for studying sebaceous lipogenesis and sebaceous gland diseases [PDF]
Experimental Dermatology, 2018 AbstractSebocytes, the major cell type in sebaceous glands, are differentiated epithelial cells that gradually accumulate lipids and eventually disrupt, releasing their content (sebum) in a secretory process known as holocrine secretion. Via the hair canal, sebum reaches the skin surface, where it has several known or postulated functions, including ...
Marlon R Schneider, Christos Zouboulis
exaly +4 more sources
Aging in the sebaceous gland. [PDF]
Front Cell Dev Biol, 2022 Sebaceous glands (SGs) originate from hair follicular stem cells and secrete lipids to lubricate the skin. The coordinated effects of intrinsic and extrinsic aging factors generate degradation of SGs at a late age. Senescence of SGs could be a mirror of the late aging of both the human body and skin.
Hou X, Wei Z, Zouboulis CC, Ju Q.
europepmc +4 more sources
Insulin and the sebaceous gland function. [PDF]
Front Physiol, 2023 Insulin affects metabolic processes in different organs, including the skin. The sebaceous gland (SG) is an important appendage in the skin, which responds to insulin-mediated signals, either directly or through the insulin growth factor 1 (IGF-1) axis.
Okoro OE +3 more
europepmc +4 more sources
Isolated primary sebaceous gland carcinoma of the bulbar conjunctiva [PDF]
American Journal of Ophthalmology Case Reports, 2022 Purpose: To report a rare case of primary sebaceous gland carcinoma of the bulbar conjunctiva without palpebral involvement. Observation: A 76-year-old male was referred to the cornea service for a suspicious lesion on the limbal conjunctiva and cornea ...
Kenneth Chang +5 more
doaj +2 more sources
Development and homeostasis of the sebaceous gland [PDF]
Seminars in Cell and Developmental Biology, 2012 The important role of epidermal appendages especially the sebaceous gland has only recently been recognized. In particular, it has been convincingly shown that normal development and maintenance of the sebaceous gland are required for skin homeostasis since atrophic sebaceous glands and disturbances in sebaceous lipid composition result in major ...
Valerie Horsley, Catherin Niemann
exaly +3 more sources
Skin single-cell transcriptomics reveals a core of sebaceous gland-relevant genes shared by mice and humans [PDF]
BMC GenomicsBackground Single-cell RNA sequencing (scRNA-seq) has been widely applied to dissect cellular heterogeneity in normal and diseased skin. Sebaceous glands, essential skin components with established functions in maintaining skin integrity and emerging ...
Torsten Thalheim, Marlon R. Schneider
doaj +2 more sources
Inguinal sebaceous gland carcinoma : A rare case report and literature review [PDF]
Rare TumorsInguinal sebaceous gland carcinoma is extremely rare, often mistaken for inflammatory skin lesions, leading to delays in diagnosis and treatment. We reported a rare clinical case of a 59-year-old male patient who presented to the hospital with a lesion ...
Khanh Ha Nguyen, Thi Thanh Trinh
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Mechanisms of Puerariae Lobatae Radix in regulating sebaceous gland secretion: insights from network pharmacology and experimental validation [PDF]
Frontiers in PharmacologyObjectiveThis research aims to explore how Puerariae Lobatae Radix regulates sebaceous gland secretion using network pharmacology, and validate its effects on important targets through animal studies.MethodsThis study utilized UPLC-EQ-MS to analyze ...
Du Yijie +7 more
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A Case of Sebaceous Adenitis and Concurrent Meibomian Gland Dysfunction in a Dog
Veterinary Sciences, 2020 Sebaceous adenitis and concurrent meibomian gland dysfunction (MGD) were diagnosed in a two-year-old mongrel dog presenting with hypotrichosis, exfoliative dermatitis and blepharitis.
Roberta Sartori, Claudio Peruccio
doaj +3 more sources
Dermato-Endocrinology, 2009 The principal activity of mature sebaceous glands is producing and secreting sebum, which is a complex mixture of lipids. Sebum composition is different among species and this difference is probably due to the function that sebum has to absolve. In human sebum there are unique lipids, such as squalene and wax esters not found anywhere else in the body ...
Mauro, Picardo +3 more
openaire +2 more sources