Results 231 to 240 of about 3,654,168 (280)

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Females and Exercise Capacity Impairment in Heart Failure: A Sex-Focused Analysis. [PDF]

J Cardiovasc Dev Dis
Lorenzo A, Ramos-Polo R, Lorenzo-Esteller L, Lin X, Barragan E, Aranda P, Boixader È, Regull F, Martín N, Ollé A, Llagostera M, José-Bazán N, Moliner P, Enjuanes C, Comin-Colet J.   +14 more
europepmc   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Direct Profiling of Extracellular Vesicle Surface Markers in Plasma: A Proof-of-Concept Study. [PDF]

Biol Cell
Clegg LA, Jensen RB, Bæk R, Mumm BH, Sørensen MK, Blauenfeldt RA, Drasbek KR, Jørgensen MM.   +7 more
europepmc   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Effects of infrared assisted refractance window drying on physicochemical and quality attributes and thermodynamic analysis of thyme (Thymus vulgaris L.). [PDF]

Sci Rep
Zomorodi S, Kaveh M, Rikan MH, Mariusz S, Dziwulska-Hunek A.   +4 more
europepmc   +1 more source

MeCP2 interacts with the super elongation complex to regulate transcription. [PDF]

Sci Adv
Sonn JY, Kim W, Iwanaszko M, Aoi Y, Li Y, Qi G, Parkitny L, Brissette JL, Weiner L, Botas J, Al-Ramahi I, Shilatifard A, Zoghbi HY.   +12 more
europepmc   +1 more source

AI-Driven Cybersecurity in IoT: Adaptive Malware Detection and Lightweight Encryption via TRIM-SEC Framework. [PDF]

Sensors (Basel)
Mutambik I.
europepmc   +1 more source

Viral zoonoses assessment in invasive rodent species from São Tomé and Príncipe. [PDF]

PLoS One
Almeida T, Matos MC, Velarde-Garcéz DA, Mata VA, Martins M, Neves C, Beja P, Lopes AM, Abrantes J.   +8 more
europepmc   +1 more source

Fast disintegrating pellets: Formulation and evaluation. [PDF]

F1000Res
Anabousi S, Naseef H, Qurt M, AbuKhalil A, Rabba A.   +4 more
europepmc   +1 more source