Results 161 to 170 of about 32,414 (208)

Rapid Water Permeation by Aramid Foldamer Nanochannels With Hydrophobic Interiors. [PDF]

Angew Chem Int Ed Engl
Farooq S, Malla JA, Nedyalkova M, Freire RVM, Mandal I, Crochet A, Salentinig S, Lattuada M, McTernan CT, Kilbinger AFM.   +9 more
europepmc   +1 more source

Cascade Therapy of Periodontitis via Sequential Release of Ribosome‐Targeting Antimicrobial Peptide and Irisin From a Multifunctional MOF‐Based System

Advanced Science, EarlyView.
This study presents a novel strategy for periodontitis treatment by co‐delivering a membrane‐ and ribosome‐targeting antimicrobial peptide GF and Irisin through a pH‐responsive metal‐organic framework. The system enables sequential release, providing rapid antibacterial action, anti‐inflammatory and antioxidative effects, as well as promoting bone ...
Yan Chen, Zheng Xu, Yunmo Xue, Shanshan Liu, Xiang Zhang, Jingyao Guo, Minhui Yao, Yue Liu, Xiaolin Lu, Jieshu Qian, Qian Ma   +10 more
wiley   +1 more source

Interplay between membranes and biomolecular condensates in the regulation of membrane-associated cellular processes. [PDF]

Exp Mol Med
Kim N, Yun H, Lee H, Yoo JY.
europepmc   +1 more source

Engineered CAR‐NKT Extracellular Vesicles Suppress Tumor Progression and Enhance Antitumor Immunity

Advanced Science, EarlyView.
TM4SF1‐nanobody engineered CAR‐natural killer T–derived extracellular vesicles (CARTM4SF1‐EVs) provide a cell‐free alternative to CAR‐NKT therapy, achieving potent, targeted antitumor activity with reduced toxicity. CARTM4SF1‐EVs induce immunogenic cell death, remodel the tumor microenvironment, and enhance CD8⁺ T‐cell antitumor immunity.
Xiaopei Hao, Chengming Qu, Yanzhao Zhou, Xiaoqian Wang, Xiangjun Qian, Xun Chen, Feng Han, Xiaokai Zhang, Yiyi Ji, Han Li, ChengWei Ju, Peng Xia, Weiwei Tang, Hao Zhuang, Jinxue Zhou   +14 more
wiley   +1 more source

Single‐Cell Morphomechanics of Prostate Cancer‐Associated Fibroblasts Identifies Distinct Features Associated with Patient Outcome

Advanced Science, EarlyView.
Cancer‐associated fibroblasts (CAFs) in prostate tumors exhibit distinct morphomechanical traits vs normal fibroblasts, including greater stiffness and volume, more elongated stress fibres, and larger and more elongated nuclei. These features, quantified through imaging and real‐time deformability cytometry, correlate with patient outcomes and can be ...
Antje Garside, Angela Jacobi, Shivakumar Keerthikumar, Vaibhav Mahajan, Michelle Richards, Birunthi Niranjan, Linda Teng, Nicholas Choo, Johannes Low Jun Wei, Gail P Risbridger, Mitchell G Lawrence, Anna V. Taubenberger   +11 more
wiley   +1 more source

The Transmembrane Glutamate Serves as a pH Sensor for Tha4 Oligomerization During Twin Arginine Transport of Proteins. [PDF]

Plants (Basel)
Weesinghe VS, New CP, Dabney-Smith C.
europepmc   +1 more source

Metal‐Supramolecular Drug Delivery System Empowered Meningeal Lymphatic Vessels‐Bridged Intracranial‐Peripheral Dual Immune Modulation for Reversing Glioblastoma Immune Suppression

Advanced Science, EarlyView.
A novel metal‐supramolecular nanoplatform (FLM@VC) enables efficient brain delivery via meningeal lymphatic vessels (MLVs), bypassing the blood‐brain barrier (BBB) through subcutaneous administration. It reprograms tumor‐associated macrophages (TAMs) and remodels the MLVs to promote DC trafficking and CD8+ T cell activation.
Chenxi Zhang, Zhongsheng Xu, Xiaowen Xu, Zening Zhang, Ranran Luo, Pengchen Ren, Yingying Luo, Qiuchi Wu, Xinyu Liu, Guodong Liu, Xiaojing He, Yun Liu   +11 more
wiley   +1 more source

The potential of plant-derived vesicles in treating periodontitis and associated systemic diseases: current advances and future directions. [PDF]

J Nanobiotechnology
Liu Z, Guo Y, Deng Y, Shao J, Huang X, Cao Z.   +5 more
europepmc   +1 more source

Ionic Highways under Multivariate‐Coupled Strategies: Ultrahigh Power Generation from Industrial Waste Liquors Using Robust COF Membranes

Advanced Science, EarlyView.
This study presents a multivariate‐coupled strategy to fabricate TB‐COF membranes with tunable charge density via uniformly distributed Bpy groups, enabling efficient ion transport and energy harvesting. The robust β‐ketoenamine‐linked structure ensures stability, achieving power outputs of 53.08 W m−2 (pH 4), 190.52 W m−2 (low‐grade heat), and 258.81 ...
Hongyan Qi, Weibo Sun, Jundong Zhong, Zhen Xing, Tingting Xu, Shuang Zhao, Haoyang Tan, Ziyi Hu, Hujun Qian, Yuchen Wu, Haibo Zhang, Jianxin Mu, Xuanbo Zhu, Lei Jiang   +13 more
wiley   +1 more source

Cardioprotection During Myocardial Infarction in Diabetic Cardiomyopathy. [PDF]

Diabetes
Alcover S, López S, Ramos-Regalado L, Muñoz-García N, Gallinat A, Suades R, Badimon L, Vilahur G.   +7 more
europepmc   +1 more source