Results 91 to 100 of about 3,149 (256)
Model‐Driven Optimization of Subcutaneous Polymer Prodrugs Achieves Cancer Remission in Mice
A pharmacokinetics/pharmacodynamics (PK/PD) model was developed to evaluate multiple dosing regimens for subcutaneously administered water‐soluble polymer prodrug for cancer therapy. The model enabled prediction of in vivo performance and contributed to the optimization of anticancer efficacy.
Anne Rodallec +5 more
wiley +1 more source
Sobre la convergencia de un método secante para ecuaciones matriciales no lineales
En este artículo desarrollamos una teoría general de convergencia de un método secante para resolver ecuaciones matriciales no lineales. Además, presentamos condiciones suficientes para que este método proporcione un algoritmo local y superlinealmente
Mauricio Macías C. +2 more
doaj
Efficiency of Ridders’ method in solving nonlinear equations using Scilab programming
The study aims to compare the efficiency of numerical methods such as Bisection, Secant, Newton-Raphson, Ridders and Halley’s methods in solving nonlinear scalar equations.
Annie Gorgey +3 more
doaj +1 more source
xx xx. ABSTRACT Stimuli‐responsive nanomaterials capable of spatiotemporal control over drug release are of nanocomposite patch (“e‐Medi‐Patch”) engineered from biodegradable polycaprolactone (PCL), graphene nanoplatelets, and a redox‐active therapeutic, niclosamide. The hierarchical composite integrates π‐π interactions between aromatic drug molecules
Santosh K. Misra +7 more
wiley +1 more source
A human microfluidic blood‐brain barrier (mBBB) model enables spatially resolved comparison of nanoparticle trafficking. Extracellular vesicles (EVs), liposomes, and nanoplastics exhibit distinct transport and disruption behaviors, revealing that membrane composition and uptake pathways govern BBB interaction.
Bryan B. Nguyen +9 more
wiley +1 more source
Thermal Processing Creates Water‐Stable PEDOT:PSS Films for Bioelectronics
Instead of using chemical cross–linkers, it is shown that PEDOT:PSS thin films for bioelectronics become water‐stable after a simple heat treatment. The heat treatment is compatible with a range of rigid and elastomeric substrates and films are stable in vivo for >20 days.
Siddharth Doshi +16 more
wiley +1 more source
Transient Charging of Mixed Ionic‐Electronic Conductors by Anomalous Diffusion
This article explores charge transport in mixed ionic‐electronic conductors (MIECs) through electrochemical impedance spectroscopy and transient current analysis. Focusing on PEDOT:PSS, WO3, and n‐doped PBDF, it uncovers the impact of anomalous diffusion via fractional modeling. The study reveals key correlations that deepen understanding and guide the
Heyi Zhang +9 more
wiley +1 more source
The Compact Conical Borehole Over-coring (CCBO) method is employed for the determination of the three-dimensional stress state in rock environments. The method utilises a strain gauge cell to quantify the deformation of over-cored rock, the deformation ...
Alice Petrlíková +5 more
doaj +1 more source
Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa +3 more
wiley +1 more source

