Results 11 to 20 of about 1,261 (178)

Standard, secant and equidistant parallels

Kartografija i geoinformacije, 2020
The paper describes a study of equidistant, standard and secant parallels in normal aspect cylindrical and conical projections. First, the explanation of cylindrical and conical projections as projections on cylindrical or conical surfaces is not recommended because it leads to misunderstanding projection properties.
Lapaine, Miljenko, de Menezes, Paulo Márcio Leal   +1 more
openaire   +2 more sources

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Experimental study on impact dynamics characteristics of coal-based solid waste cemented backfill

Meitan xuebao
The impact dynamics of coal-based solid waste cemented backfill are the basis for the research on the prevention and control of rock burst by underground filling.
Ke YANG, Xiaowu FENG, Xiang HE, Jiqiang ZHANG, Shuxin HE, Xiang YU, Longqiang WEI, Zilong ZHANG   +7 more
doaj   +1 more source

Identification of the plant mitochondrial OrfX protein: A mass spectrometry approach

FEBS Letters, EarlyView.
The mitochondrial genome of plants contains an open reading frame, orfx, which encodes a rare protein that has so far escaped mass spectrometric detection. The protein resembles the c‐subunit of bacterial twin‐arginine‐motif‐dependent protein translocases (TatC).
Matthias Döring, Jan de Jonge, Hans‐Peter Braun, Nils Rugen   +3 more
wiley   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

Multi-Scale Damage Evolution of Soil-Rock Mixtures Under Freeze–Thaw Cycles: Revealed by Electrochemical Impedance Spectroscopy Testing and Fractal Theory

Fractal and Fractional
The response of the microscopic structure and macroscopic mechanical parameters of SRM under F–T cycles is a key factor affecting the safety and stability of engineering projects in cold regions.
Junren Deng, Lei Wang, Guanglin Tian, Hongwei Deng   +3 more
doaj   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Mechanical Performance and Stress–Strain Modelling of Coal Ash Brick Masonry Assemblages Under Flexural Loading

Advances in Civil Engineering
The increasing demand for sustainable construction materials has prompted the utilisation of industrial by-products such as coal ash (CA) in masonry units.
Vidhya Kumarasamy, Sudharsan Narayanasamy, K. Yuvaraj, G. K. Arunvivek, Pramod Kumar, Worku Gadisa   +5 more
doaj   +1 more source