Results 1 to 10 of about 801 (115)
Second-generation antipsychotics - a panacea?
South African Journal of Psychiatry, 2004 NO ABSTRACT ...
Paul D Carey, Dan Stein, Robin Emsley
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Biomedicines, 2022 Schizophrenia (SCZ) is a complex psychiatric disorder of multifactorial origin, in which both genetic and environmental factors have an impact on its onset, course, and outcome.
Olga Płaza +5 more
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Antioxidant Properties of Second-Generation Antipsychotics: Focus on Microglia [PDF]
Pharmaceuticals, 2020 Recent studies suggest a primary role of oxidative stress in an early phase of the pathogenesis of schizophrenia and a strong neurobiological link has been found between dopaminergic system dysfunction, microglia overactivation, and oxidative stress ...
Giuseppe Caruso +5 more
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Medicina, 2019 Objectives: The aim of this study was to determine the incidence of metabolic syndrome in patients treated with second-generation antipsychotics (SGAs).
Osama Abo Alrob +7 more
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First- and Second-Generation Antipsychotics [PDF]
The Canadian Journal of Psychiatry, 2010 Joseph P McEvoy, MD1; Daniel Zigman, MD2; Howard C Margolese, MD, CM, MSc, FRCPC3 Can J Psychiatry. 2010;55(3):144-149. Are SGAs Better Than FGAs? No The FGAs are a group of drugs with the common pharmacological action of D2 blockade. D2 blockade offers impressive (relative to placebo) but limited therapeutic benefit in the treatment of acute psychotic
Joseph P, McEvoy +2 more
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Archives of Mental Health, 2020 Introduction: The prevalence of metabolic syndrome is more in patients with schizophrenia receiving first- and second-generation antipsychotics. Aim and Objectives: The aim is to study the prevalence of metabolic syndrome in patients with schizophrenia ...
Dinesh Panati +3 more
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Are Second Generation Antipsychotics a Distinct Class? [PDF]
Journal of Psychiatric Practice, 2008 Second generation antipsychotic medications have become synonymous with "atypicality." To support the clinical lore of equivalent efficacy with reduced risk of extrapyramidal symptoms, clinical trials have overwhelmingly chosen a high-potency first-generation antipsychotic (e.g., haloperidol) as a comparator.
Caroline, Bonham, Christopher, Abbott
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Combination treatment with second generation antipsychotics other than clozapine
European Psychiatry, 2021 Background Antipsychotic combination treatment without clozapine is common in the treatment of schizophrenia patients worldwide, despite clinical guidelines generally do not recommend such practice.
C. Schmidt-Kraepelin
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Second-generation antipsychotics and pregnancy complications [PDF]
European Journal of Clinical Pharmacology, 2019 Abstract Purpose To study if second-generation antipsychotic (S-GA) use during pregnancy is associated with an increased risk of pregnancy and neonatal complications. Methods A population-based birth cohort study using national register data extracted from the “Drugs and Pregnancy” database in Finland, years 1996–2016.
Maria Ellfolk +6 more
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Antipsychotic use in a resource-limited setting: Findings in an Eastern Cape psychiatric hospital
South African Journal of Psychiatry, 2017 Background: Second-generation antipsychotics (SGAs) are commonly prescribed despite the fact that large, naturalistic studies have failed to show superior efficacy and tolerability when compared with first-generation antipsychotics (FGAs). In addition to
Ingrid Eloff +2 more
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