Results 131 to 140 of about 229,810 (202)

CPL‐Diff: A Diffusion Model for De Novo Design of Functional Peptide Sequences with Fixed Length

Advanced Science, EarlyView.
This study presents a diffusion model for generating functional peptide sequence lengths using mask control. The model can generate antimicrobial, antifungal, and antiviral peptides with specific lengths on demand. The model learns the structure of peptides better and generates peptides with better physicochemical properties, and the model has good ...
Zhenjie Luo, Aoyun Geng, Leyi Wei, Quan Zou, Feifei Cui, Zilong Zhang   +5 more
wiley   +1 more source

Steering veridical large language model analyses by correcting and enriching generated database queries: first steps toward ChatGPT bioinformatics. [PDF]

Brief Bioinform
Cinquin O.
europepmc   +1 more source

ProteoSeeker: A Feature‐Rich Metagenomic Analysis Tool for Accessible and Comprehensive Metagenomic Exploration

Advanced Science, EarlyView.
ProteoSeeker is a new metagenomic analysis tool that accelerates protein discovery. By automating key steps, it reduces computational complexity and enables comprehensive dataset analysis, performing protein identification, screening based on user‐defined protein families, and taxonomic analysis.
Georgios Filis, Dimitra Bezantakou, Konstantinos Rigkos, Despina Noti, Pavlos Saridis, Dimitra Zarafeta, Georgios Skretas   +6 more
wiley   +1 more source

Development of an automated CBCT-based simulation-free platform for expedited palliative radiotherapy on a conventional linear accelerator. [PDF]

J Appl Clin Med Phys
Tegtmeier RC, Clouser EL, Chen Q, Buckey CR, Chungbin SJ, Kutyreff CJ, Aguilar JS, Labbe AL, Horning BL, Rule WG, Vora SA, Rong Y.   +11 more
europepmc   +1 more source

Advancements in Bio‐Integrated Flexible Electronics for Hemodynamic Monitoring in Cardiovascular Healthcare

Advanced Science, EarlyView.
This review explores the cutting‐edge development of bio‐integrated flexible electronics for real‐time hemodynamic monitoring in cardiovascular healthcare. It covers key physiological indicators, innovative sensing mechanisms, and materials considerations. This paper highlights the application of both invasive and non‐invasive devices in cardiovascular
Ke Huang, Zhiqiang Ma, Bee Luan Khoo
wiley   +1 more source

Reinforcement learning for mutation operator selection in automated program repair. [PDF]

Autom Softw Eng
Hanna C, Blot A, Petke J.
europepmc   +1 more source

Deciphering the Metabolic Impact and Clinical Relevance of N‐Glycosylation in Colorectal Cancer through Comprehensive Glycoproteomic Profiling

Advanced Science, EarlyView.
The comprehensive proteomic and N‐glycoproteomic analyses of 45 colorectal cancer tissues with matched normal adjacent tissues identified 7125 intact N‐glycopeptides from 704 glycoproteins. A glycosylation site‐protein function network revealing metabolic dysregulation is constructed and a model differentiating tumors from normal tissues is developed ...
Guobin Liu, Lu Chen, Jingxiang Zhao, Yue Jiang, Yarong Guo, Xiang Mao, Xuelian Ren, Kun Liu, Qi Mei, Qunyi Li, He Huang   +10 more
wiley   +1 more source

ChatGPT, Python, and Microsoft Excel. [PDF]

J Med Libr Assoc
Sbampato K, Arruda H, Silva ÉR.
europepmc   +1 more source

Single‐Cell Analysis Clarifies Pathological Heterogeneity in Tenosynovial Giant Cell Tumor and Identifies Biomarkers for Predicting Disease Recurrence

Advanced Science, EarlyView.
MP3 tumor cells, a specific subpopulation of tumor cells in D‐TGCT, regulated the differentiation of CD34+ Fbs into MMP3+ Fbs and APOE+ Fbs through COL6A3 − (ITGAV + ITGB8) interaction. APOE+ Fbs activated IL‐1B+CCL20+ Mφs through the CXCL12/CXCR4 axis. IL‐1B+CCL20+ Mφs and MMP3+ Fbs participated in the local invasion of D‐TGCT.
Yubin Xie, Chen Chen, Fei Wu, Yiman Peng, Jing Su, Yang Zhao, Hongjie Huang, Zhong Alan Li, Yin Pei, Wencui Li, Yi He, Tianchen Xue, Chenxi Cao, Sui Peng, Xin Zhang, Weidong Song   +15 more
wiley   +1 more source

"MoSpec": A customized and integrated system for model development, verification and validation. [PDF]

PLoS One
Pompa M, Panunzi S, Borri A, D'Orsi L, De Gaetano A.   +4 more
europepmc   +1 more source