Results 151 to 160 of about 29,565 (201)

NDST3‐Induced Epigenetic Reprogramming Reverses Neurodegeneration in Parkinson's Disease

open access: yesAdvanced Science, EarlyView.
NDST3‐mediated epigenetic reprogramming revitalizes neuronal circuits in the substantia nigra and striatum to halt dopaminergic neuron degeneration and restore motor function in Parkinson's disease models. This strategy promotes neuronal maintenance and functional recovery, highlighting NDST3's therapeutic potential in neurodegenerative disorders ...
Yujung Chang   +18 more
wiley   +1 more source

Data‐Driven Fatigue Prediction of Superalloys: A Novel Strategy Integrating Transfer Learning and Partial Label Learning for Addressing Ambiguous Data

open access: yesAdvanced Science, EarlyView.
A novel machine learning strategy tackles ambiguous compositional data to predict superalloy fatigue. By integrating partial label with transfer learning and enriching features through thermodynamic calculations, this approach achieves superior accuracy and interpretability.
Haopeng Lv   +10 more
wiley   +1 more source

ZNRD2 Mediated Nucleoprotein Aggregation Impairs Respiratory Syncytial Virus Replication

open access: yesAdvanced Science, EarlyView.
During RSV infection, nucleoprotein (N) forms RNA‐bound oligomers. The host protein ZNRD2 binds to these oligomers, promoting their transition into insoluble aggregates. These aggregates simultaneously sequester functional N to restrict viral production and disrupt chaperonin assembly quality control by interfering with ZNRD2's role as an adaptor ...
Haiwu Zhou   +8 more
wiley   +1 more source

Artificial Tactile Perception System for Exploring Internal and External Features of Objects via Time‐Frequency Features

open access: yesAdvanced Science, EarlyView.
By engaging in different active exploration behaviors, the tactile perception system can generate distinct signal modes, enabling the application of targeted decoding strategies for efficient and accurate perception of both external and internal object features.
Yuanzhi Zhou   +8 more
wiley   +1 more source

MCP-enabled LLM for meta-optics inverse design: leveraging differentiable solver without LLM expertise. [PDF]

open access: yesNanophotonics
Huang Y   +7 more
europepmc   +1 more source

Wearable and Implantable Devices for Continuous Monitoring of Muscle Physiological Activity: A Review

open access: yesAdvanced Science, EarlyView.
Recent advances in materials and device engineering enable continuous, real‐time monitoring of muscle activity via wearable and implantable systems. This review critically summarizes emerging technologies for tracking electrophysiological, biomechanical, and oxygenation signals, outlines fundamental principles, and highlights key challenges and ...
Zhengwei Liao   +4 more
wiley   +1 more source

Device to Circuit Co‐Design Utilizing High‐Performance PEALD Indium‐Gallium‐Zinc Oxide Thin‐Film Transistor Enabling Technology Node Scaling in Monolithic 3D Systems

open access: yesAdvanced Science, EarlyView.
This article presents a holistic investigation of M3D‐compatible oxide semiconductor technology using PEALD‐fabricated IGZO TFTs, spanning device‐level characterization, TCAD Modeling, circuit design, and scaled‐node projections. It demonstrates high field‐effect mobility (up to 116.35 cm2 V−1·s−1), robust reliability (△VTH < 0.15 V), low variation ...
Wenhui Wang   +11 more
wiley   +1 more source

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