Results 11 to 20 of about 104,177 (219)
Second-order productivity, second-order payoffs, and the Owen value
, 2022 We introduce the concepts of the components' second-order productivities in cooperative games with transferable utility (TU games) with a coalition structure (CS games) and of the components' second-order payoffs for one-point solutions for CS games as ...
Tido Takeng, Rodrigue, Casajus, André
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Overshadowed by popularity: The value of second-tier stars in European football [PDF]
, 2022 Superstars in European football are exceptionally talented and enjoy celebrity status. While second-tier stars, i.e., players barely below superstar status, lack popularity, their marginal contribution to team performance on the pitch relative to that of
Flepp, Raphael; https://orcid.org/ +2 more
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Overshadowed by Popularity: The Value of Second-Tier Stars in European Football [PDF]
, 2023 While second-tier stars lack popularity compared to superstars, their marginal contribution to team performance on the pitch relative to that of superstars is unknown.
Flepp, Raphael; https://orcid.org/ +2 more
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Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Higher order sigma point filter: A new heuristic for nonlinear time series filtering [PDF]
, 2013 In this paper we present some new results related to the higher order sigma point filter (HOSPoF), introduced in [1] for filtering nonlinear multivariate time series. This paper makes two distinct contributions.
Date, P, Ponomareva, K
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Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
Restless bandit marginal productivity indices II: multiproject case and scheduling a multiclass make-to-order/-stock M/G/1 queue [PDF]
, 2004 This paper develops a framework based on convex optimization and economic ideas to formulate and solve approximately a rich class of dynamic and stochastic resource allocation problems, fitting in a generic discrete-state multi-project restless bandit ...
Niño-Mora, José, Niño Mora, José
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Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source