Results 151 to 160 of about 12,595,460 (288)

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Separating stroke and acute unilateral vestibulopathy using history, examination and vestibular tests: a machine learning approach. [PDF]

J Neurol
Wang C, Chaturvedi K, Nham B, Reid N, Bradshaw AP, Rosengren SM, Black DA, Bein KJ, Halmagyi GM, Braytee A, Bharathy GK, Prasad M, Welgampola MS.   +12 more
europepmc   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

An integrated model to explore Chinese Gen Z consumers' second-hand clothing purchase intention. [PDF]

Front Psychol
Zhou Q, Ji X, Cai L, Zhou L.
europepmc   +1 more source

Tractor Testing; Belt Test; Allis Chalmers

, 1948
Official belt test no. 397 Allis-Chalmers HD19." The Allis-Chalmers HD-19 crawler on berlt power test inside the tractor test lab. Technician Joe Flamm stands measuring belt speed with a hand-held tachometer.
Nebraska Tractor Test Laboratory
core  

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Improving Severe Combined Immunodeficiency and Cystic Fibrosis Newborn Screening by Replacing Current Tests with First-Tier Targeted Gene Sequencing. [PDF]

Int J Neonatal Screen
Shum BOV, Pretorius C, Henner I, Basar E, Wilgen U, Bennett G, Ungerer JPJ.   +6 more
europepmc   +1 more source

Test no. 394 Massey-Harris 55. 1948.

, 1948
Three-quarter view from the front of the Massey-Harris tractor on the test track.
Nebraska Tractor Test Laboratory
core  

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

National Essential Diagnostics List development as an opportunity to expand frontline diagnostic testing at barangay health stations in the Philippines. [PDF]

Trop Med Health
Kanamori S, Evangelista NM, Egami Y, Marayag NG, Cruz-Yañez S, Dela Resma Villanueva AF, Uechi M, Kiyohara H, Dolor MKYD, Ramones RAJ, Duazo AA, Fujita M.   +11 more
europepmc   +1 more source