Results 211 to 220 of about 12,595,460 (288)

Key Outcomes from a Stakeholder Workshop on Genomic Newborn Screening: Recommended Next Steps for the Integration of Genomics into Public Health Programs.

Public Health Genomics
Smits SG, Duintjer AJ, van Duyvenvoorde HA, Rodenburg W, van der Burg M, Henneman L, Blom M.   +6 more
europepmc   +1 more source

Single-step immunoblot tests with recombinant protein antigens for detecting IgG and IgM antibodies in Lyme disease. [PDF]

Microbiol Spectr
Shah JS, Liu S, Calalo-Ramos C, Myint M, Lee O, Cruz I, Horn EJ, Ramasamy R.   +7 more
europepmc   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

P057: Reducing the false positive for guanidinoacetate methyltransferase enzyme deficiency in newborns by the addition of a second tier UPLC-MS/MS test

Genetics in Medicine Open
Jun Qiang Zhou, Kuldeep Dhillon, Jeffrey Aduviso, Long Nguyen, Alexander Cruz, Daniel Simon, Jamie Matteson, Sarah Carter, Tracey Bishop, Rajesh Sharma   +9 more
doaj   +1 more source

From signal to construct evidence: multimodal consumer-wearable sensing in real general-aviation flight. [PDF]

Front Neuroergon
Xu R, Cao S, Barnett-Cowan M, Bulbul G, Kearns S, Niechwiej-Szwedo E.   +5 more
europepmc   +1 more source

Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells

FEBS Open Bio, EarlyView.
To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai, Yong Xu, Jingjing Ma, Ratchanee Duangrat, Chen Yan, Jingyan Liang, Hua Wei, Bin Jiang, Tao‐Sheng Li   +8 more
wiley   +1 more source

21-Deoxycortisone: A Novel Sensitive and Specific Newborn Screening Marker for Congenital Adrenal Hyperplasia. [PDF]

Int J Neonatal Screen
de Hora M, Heather N, Webster D, Albert BB, Hofman P.   +4 more
europepmc   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

DeepExoMir: A Reproducible RNA Language Model Framework for CLIP-Seq-Supported MicroRNA Target-Site Prioritization. [PDF]

Int J Mol Sci
Lin WH, Hsiung CN, Lien WY, Sieber M.
europepmc   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source