A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo +7 more
wiley +1 more source
The second demographic transition in Japan: a review of the evidence
AbstractDespite a half century of below-replacement fertility, Japan is typically not included in discussions and evaluations of the second demographic transition (SDT), a widely referenced framework for understanding family changes and attitudinal shifts associated with very low fertility. I address this limitation by drawing upon a range of published
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Pathways and pitfalls: a qualitative study of student experiences in biomedical science education
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell +8 more
wiley +1 more source
Is the Second Demographic Transition a useful concept for demography? [PDF]
It is generally agreed that the Second Demographic Transition is characterised by (1) a trend toward less committed and more fragile relations between men and women, and (2) the delayed and less likely transition to parenthood and a sharp re duction of higher-order births, or, in other words, postponement of marriage and first birth, more cohabitation ...
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Russian Federation: From the first to second demographic transition
The demographic transition in Russia was accelerated by several social cataclysms during the "Soviet type" modernization. Frequent changes in the timing of births and marriages engendered a mass "abortion culture".
Sergei Zakharov
doaj
First conjugal union and religion: Signs contrary to the Second Demographic Transition in Brazil?
Background: Two of main characteristics of the Latin American conjugal union pattern are the early entry into first union and the increasing proportion of informal unions.
Ana Paula Verona +3 more
doaj +1 more source
Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley +1 more source
Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss +12 more
wiley +1 more source
Ageing in European post-communist countries – is it a threat to the welfare system?
The aim of the study was to diagnose the current and projected pace of ageing in the societies of European post-communist countries from the point of view of its being an increasing economic burden on the economically active population.
Michalski Tomasz, Stępień Joanna
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Is the second demographic transition the relevant concept for European countries? [PDF]
The theory of second demographic transition is particularly unique in trying to capture both the transformation of reproductive behaviour and a change in the attitudes towards new forms of partnership life and a new reproductive pattern. This study has set as its target to find out to what degree second demographic transition can be used as an ...
Helena Polesná, Jiřina Kocourková
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