Results 61 to 70 of about 1,276,307 (288)
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Zanco Journal of Pure and Applied Sciences, 2021 Three methods for simultaneous estimation of diclofenac sodium and pridinol mesylate have been developed. First method is the application of the Q–analysis (absorbance ratio) method, the wavelengths selected were 265nm (isosbestic point) and 285nm (λmax
Hemn Khalid Qadir, Hemn Abdul Qader
doaj
Molecular bases of circadian magnesium rhythms across eukaryotes
FEBS Letters, EarlyView.Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
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Some New Variants of Cauchy's Methods for Solving Nonlinear Equations
Journal of Applied Mathematics, 2012 We present and analyze some variants of Cauchy's methods free from second derivative for obtaining simple roots of nonlinear equations. The convergence analysis of the methods is discussed. It is established that the methods have convergence order three.
Tianbao Liu, Hengyan Li
doaj +1 more source
A second derivative method of resistivity sounding
Journal of Earth System Science, 1982 The second vertical derivatives of gravity and magnetic potential are widely used in geophysical prospecting because of their better resolution. On the same basis an attempt has been made to obtain the expressions for the second vertical derivative of the electrical potential and to compute its nature for comparison.
Murali Sabnavis, K. K. Sharma
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Derivation of a Numerical Method with Free Second-order Derivatives
International Journal of Pure Mathematics, 2022 We have proposed the second-derivative-free numerical method and determined the control parameters to converge cubically. In addition, we have developed the order of convergence and the asymptotic error constant. Applying this iterative scheme to a variety of examples, numerical results have shown a successful asymptotic error constants with cubic ...
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Numerical Methods for Solving Fractional Differential Equations [PDF]
, 2018 Department of Mathematical SciencesIn this thesis, several efficient numerical methods are proposed to solve initial value problems and boundary value problems of fractional di???erential equations.
Kim, Keon Ho
core
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source