Results 111 to 120 of about 21,689 (264)

Neonatal developmental and epileptic encephalopathy with movement disorder and arthrogryposis: A shared phenotype across brain‐expressed sodium channelopathies

open access: yesEpilepsia, EarlyView.
Abstract Objective Neonatal developmental and epileptic encephalopathy with movement disorder and arthrogryposis (NDEEMA) represents the most severe end of the gain‐of‐function (GOF) SCN1A disorder spectrum. Sporadic cases of congenital arthrogryposis have also been reported in individuals with SCN2A‐, SCN3A‐, and SCN8A‐related developmental and ...
Sopio Gverdtsiteli   +43 more
wiley   +1 more source

[<sup>18</sup>F]-Fluciclovine or [<sup>68</sup>Ga]-PSMA-11 Molecular Imaging To Guide Dose Escalation of Salvage Radiotherapy After Radical Prostatectomy for Prostate Cancer: The EMPIRE-2 Trial. [PDF]

open access: yesEur Urol
Jani AB   +20 more
europepmc   +1 more source

Evaluation of the Adequacy of Design Specifications for Nonstructural Components in a Reticular Structure

open access: yesEarthquake Engineering &Structural Dynamics, EarlyView.
ABSTRACT Nonstructural components (NSCs) installed in large‐span reticular structures were frequently severely damaged during earthquakes, even when the primary structure remained intact. Existing seismic design specifications for NSCs were predominantly developed for upright structures such as multi‐storey buildings and offer no guidance for reticular
Xudong Zhi   +6 more
wiley   +1 more source

An Efficient Quasi‐Static Condensation‐Based Framework for Seismic Analysis of Multi‐Supported Secondary Structures

open access: yesEarthquake Engineering &Structural Dynamics, EarlyView.
ABSTRACT Multi‐supported non‐structural components (NSCs) are prone to seismic damage, yet their response prediction remains challenging when support motions are spatially incoherent. This study proposes an enhanced quasi‐static condensation (EQSC) method for linear, lightweight, dynamically detuned multi‐supported NSCs under the neglect of primary ...
Duozhi Wang   +5 more
wiley   +1 more source

Concept, Tests, and Optimum Design of Novel Negative Stiffness Friction Dampers for Seismic Protection of Long‐Span Bridges

open access: yesEarthquake Engineering &Structural Dynamics, EarlyView.
ABSTRACT Viscous dampers (VDs) are widely used to mitigate the excessive responses of long‐span bridges. However, VDs face some intricate challenges in engineering practices, including high damping coefficient requirement, potential base shear amplification and tremendous damping force under high velocity. To address these issues, this study develops a
Ruisheng Ma   +5 more
wiley   +1 more source

Weak‐Story Mitigation and Drift Redistribution in Moment‐Resisting Frames Using Stepping Rocking Walls

open access: yesEarthquake Engineering &Structural Dynamics, EarlyView.
ABSTRACT This study investigates the seismic response of moment‐resisting frames retrofitted with a stepping rocking wall, with emphasis on weak‐story mitigation and residual drift reduction under both ordinary and pulse‐like ground motions. Nonlinear response‐history analyses are conducted on 9‐story and 20‐story SAC Los Angeles frames.
Mehrdad Aghagholizadeh
wiley   +1 more source

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