Results 201 to 210 of about 7,071,070 (299)

The Second Generation

The American Biology Teacher, 1998
openaire   +1 more source

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

Molecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

Dietary restriction induces persistent multigenerational phenotypic effects in Phytoseiulus persimilis. [PDF]

Pest Manag Sci
Chen X, Zhang K, Han X, Xu Y, Zhang ZQ.
europepmc   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

Field and Laboratory Studies for Predicting Annual Generations of <i>Spodoptera littoralis</i> (Boisd.) Using Sex Pheromone Traps and Cumulative Heat Unit Measurements in Egypt. [PDF]

Insects
Ahmed AMM, Andrade-Yucailla V, Allam EAY, Saad MAA, Manaa SH, Dahi HF, Yones MS, Alcocer-Quishpe F, Barros-Rodríguez M.   +8 more
europepmc   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

Transgenerational chromosome repair in the asexual bdelloid rotifer <i>Adineta vaga</i>. [PDF]

Sci Adv
Houtain A, Dupré ML, Hespeels B, Nicolas É, Simion P, Virgo J, Heuskin AC, Lenormand T, Hallet B, Van Doninck K.   +9 more
europepmc   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

Molecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault, Capucine Heraud, Mélissa Correia de Oliveira, Véronique Neaud, Valérie Valesco, Valérie Prouzet‐Mauleon, Béatrice Turcq, Jean‐William Dupuy, Anne‐Aurélie Raymond, Sabrina Croce, Frédéric Saltel, Valérie Lagrée, Violaine Moreau   +12 more
wiley   +1 more source

Paracetamol Responses Depend on Temperature, Life Stage, and Genetic Background in <i>Drosophila melanogaster</i> Across Generations. [PDF]

Medicines (Basel)
Hundebøl BNRG, Sørensen JG.
europepmc   +1 more source