Results 21 to 30 of about 279,889 (309)

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

Targeting Intracellular Calcium Stores Alleviates Neurological Morbidities in a DFP-Based Rat Model of Gulf War Illness [PDF]

open access: yes, 2019
Gulf War Illness (GWI) is a chronic multi-symptom disorder afflicting the veterans of the First Gulf War, and includes neurological symptoms characterized by depression and memory deficits.
Blair, Robert   +3 more
core   +1 more source

Diffusion Spectrum Imaging Maps Early Axonal Loss and a Unique Progressive Signal in Neuronal Intranuclear Inclusion Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To delineate specific in vivo white matter pathology in neuronal intranuclear inclusion disease (NIID) using diffusion spectrum imaging (DSI) and define its clinical relevance. Methods DSI was performed on 42 NIID patients and 38 matched controls.
Kaiyan Jiang   +10 more
wiley   +1 more source

Covid-19: End of the beginning?

open access: yesGeospatial Health, 2020
The limited case cluster of atypical pneumonia detected in central China in December 2019, now known as Coronavirus Disease 2019 (Covid-19), converted into a million confirmed cases worldwide in only 10 weeks.
Robert Bergquist, Anna-Sofie Stengaard
doaj   +1 more source

Assessment of the Conservation Value of Abandoned Land on Gogland Island, Baltic Sea

open access: yesLand, 2023
Gogland Island, located in the Gulf of Finland in the Baltic Sea, was densely populated in the past but has been nearly abandoned since the Second World War. The self-restoration of wildlife takes place there.
Igor Popov   +2 more
doaj   +1 more source

NATO ADAPTATION AND TERRORISM, AL-QAIDA SECURITY IMPLICATION TO THE BALKAN REGION [PDF]

open access: yes, 2014
Although the Cold War ended without a major war, post-Cold War period started with regional wars in Balkans and Middle East. These wars cost to the not only human causalities and suffers but also collateral, environmental damages.
Soygeniş, İsmail Hakkı
core  

Structure–Function Decoupling of the Sensorimotor and Default Mode Networks in Black Americans With MS

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Multiple sclerosis (MS) exhibits racially disparate rates of disease progression. Black people with MS (B‐PwMS) experience a more severe disease course than non‐Hispanic White people with MS (NHW‐PwMS). Here we investigated structural and functional connectivity as well as structure–function decoupling in the ...
Emilio Cipriano   +11 more
wiley   +1 more source

MATERNAL MORTALITY IN BASRAH HOSPITALS; AN OVERVIEW OF THE LAST TWO DECADES [PDF]

open access: yesBasrah Journal of Surgery, 2006
This study aimed to determine the MMR in Basra hospitals for 20 years (1983-2002), to determine the main causes of maternal deaths with regards to direct, indirect & fortuitous causes & to verify the impact of major events including wars & sanction on ...
Salman K Ajlaan   +3 more
doaj   +1 more source

The Ethics of the Vietnam War [PDF]

open access: yes, 2017
Although the Vietnam Conflict was not conducted in an entirely ethical manner, the war provided a tangible example of the extent of Kennan’s containment theory and its effect on the United States in the twentieth ...
Ewing, Samuel
core   +1 more source

Atomic Size Misfit for Electrocatalytic Small Molecule Activation

open access: yesAdvanced Functional Materials, EarlyView.
This review explores the application and mechanisms of atomic size misfit in catalysis for small molecule activation, focusing on how structural defects and electronic properties can effectively lower the energy barriers of chemical bonds in molecules like H2O, CO2, and N2.
Ping Hong   +3 more
wiley   +1 more source

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