Results 51 to 60 of about 4,766,126 (305)
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Fennia: International Journal of Geography, 2011 Cross-border and international second home ownership is a worldwide phenomenon and growing in popularity as people seek for desirable environments further away than before.
Kati Pitkänen
doaj +2 more sources
Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae
FEBS Open Bio, EarlyView.Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj +3 more
wiley +1 more source
, 2023 As a unique form of rural-urban transition settlement in China’s rapid urbanization process, the “urban village” plays a very distinctive part in promoting urbanization, being a transit point for many rural people entering urban areas. The term “informal employment migrants” usually refers to those people, who have no formal employment status and work ...
openaire +1 more source
FEBS Open Bio, EarlyView.Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley +1 more source
Resorts, second home owners and distance: a case study in northern Finland
Fennia: International Journal of Geography, 2010 One of the most important factors for the site selection of a second home is the space-time dimension. For example, the popularity of second home tourism in the hinterland of population centres is based on the short distance between second homes and the ...
Pekka Kauppila
doaj +2 more sources
My Second Home, Basa Village [PDF]
, 2014 Article for Synchronized Chaos about the author’s journeys to Basa Village in ...
Rasley, Jeff
core +1 more source
Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control
FEBS Open Bio, EarlyView.Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada +5 more
wiley +1 more source
PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines
FEBS Open Bio, EarlyView.Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart +7 more
wiley +1 more source
Interpretable Housing for Freedom of the Body: The Next Generation of Flexible Homes [PDF]
, 2013 If we have gone through the first generation of housing design that pursued functional optimization, ergonomics, and circulation efficiency during the last century, now we are living in the second generation where more advanced goals, such as universal ...
Kim, Chang Sung, Seo, Kyung Wook
core +1 more source