Results 211 to 220 of about 1,362,599 (307)

Model‐Driven Optimization of Subcutaneous Polymer Prodrugs Achieves Cancer Remission in Mice

Advanced Healthcare Materials, EarlyView.
A pharmacokinetics/pharmacodynamics (PK/PD) model was developed to evaluate multiple dosing regimens for subcutaneously administered water‐soluble polymer prodrug for cancer therapy. The model enabled prediction of in vivo performance and contributed to the optimization of anticancer efficacy.
Anne Rodallec, Randy Lee, Jingming Cao, Sophie Marolleau, Julien Nicolas, Sébastien Benzekry   +5 more
wiley   +1 more source

Transmission pathways during high-contact care activities in nursing homes: a high-fidelity simulation study with surrogate markers. [PDF]

Infect Control Hosp Epidemiol
Gannon PR, Dotto VR, Burke KB, Regina R, Jacob JT, Mumma JM.   +5 more
europepmc   +1 more source

A Physiological Microfluidic Blood–Brain‐Barrier Model for In Vitro Study of Nanoparticle Trafficking and Accumulation

Advanced Healthcare Materials, EarlyView.
A human microfluidic blood‐brain barrier (mBBB) model enables spatially resolved comparison of nanoparticle trafficking. Extracellular vesicles (EVs), liposomes, and nanoplastics exhibit distinct transport and disruption behaviors, revealing that membrane composition and uptake pathways govern BBB interaction.
Bryan B. Nguyen, Neona M. Lowe, Sophia Kellogg, Kuan‐Wei Huang, Hannah O'Toole, Elizabeth J. Hale, Venktesh S. Shirure, Bhupinder S. Shergill, Steven C. George, Randy P. Carney   +9 more
wiley   +1 more source

Social inequities in the transition to environmentally optimized commuting. [PDF]

Sci Rep
Niedzielski MA, Hu Y.
europepmc   +1 more source

Opinion: Gavage Administration of MXene as a Route‐Specific Alternative to Intravenous Injection into the Bloodstream of Laboratory Animals for Reducing Systemic Nanotoxicity Risks in Immunosuppression and Post‐Transplantation Models with Bile Acid Modification

Advanced Healthcare Materials, EarlyView.
Recent studies reported immunosuppressive properties of specific MXene nanomaterials. Their intravenous injection into the bloodstream of laboratory animals has been a common delivery method to suppress systemic inflammation and prevent transplant rejection.
Alireza Rafieerad, M. Akif Rahman, Ahmad Amiri   +2 more
wiley   +1 more source

Pain and Pain Management in Austrian Nursing Home Residents' Daily Lives: A Qualitative Study Guided by an Integrated Quality of Life Model for Older Adults. [PDF]

Nurs Health Sci
Pichler E, Eglseer D, Schoberer D, Lohrmann C, Zwakhalen S, Hoedl M.   +5 more
europepmc   +1 more source

Epidermal Patch Technologies for Integrated Healthcare and Infection Management

Advanced Healthcare Materials, EarlyView.
Epidermal patches have evolved from simple wound coverings into multifunctional, skin‐conformable platforms integrating drug delivery, biosensing, and therapeutic functionalities. This review highlights their material innovations, fabrication strategies, and intelligent designs, including hydrogels, microneedles, and flexible electronics, while ...
Yuqi Wang, Atakan Tevlek, Pawel L. Urban, Boaz Mizrahi, Onome Ejeromedoghene, Roshan Deen, Yuanjing Lin, Jagan Mohan Dodda   +7 more
wiley   +1 more source

Fully Wireless and Flexible Valves for Multiplexed and Prolonged Intravesical Liquid Release

Advanced Healthcare Materials, EarlyView.
A fundamental mechanism for the simultaneous control of multiple magnetic valves is reported in a miniature soft robotic patch for intravesical drug delivery, enabling fully wireless and programmable liquid release. Integrated with a bioadhesive interface and induction‐coupling‐based liquid volume sensing, the soft robotic patch is promising to enable ...
Boyang Xiao, Yi Zhu, Yusheng Wang, Janene M. Pierce, Jeffrey J. Tosoian, Xiaoguang Dong   +5 more
wiley   +1 more source

Exploring Personal Support Worker Education, Recruitment, and Retention in Long-Term Care Homes in Ontario, Canada: Protocol for a Mixed Methods Study.

JMIR Res Protoc
Kernoghan A, Just D, Tong CE, Sheiban Taucar L, Kirkwood D, Smith BJ, Living Classroom Team.   +6 more
europepmc   +1 more source

Characterizing household air pollutant concentrations associated with an electrification program in the rural San Joaquin Valley. [PDF]

Environ Res Health
Johnson M, Kearns KA, Rivera J, Jones SM, Tryner J, Miller H, Ghosh A, Aragon MF, Daouda M, Pillarisetti A, Tyner T.   +10 more
europepmc   +1 more source