Results 41 to 50 of about 1,362,599 (307)

Sensor function virtualization to support distributed intelligence in the internet of things [PDF]

, 2015
It is estimated that-by 2020-billion devices will be connected to the Internet. This number not only includes TVs, PCs, tablets and smartphones, but also billions of embedded sensors that will make up the "Internet of Things" and enable a whole new range
Demeester, Piet, Hoebeke, Jeroen, Moerman, Ingrid, Teklemariam, Girum Ketema, Van den Abeele, Floris   +4 more
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Tourism development and sustainability in French Cerdagne

Revue de Géographie Alpine, 2009
The combined effect of problems related toclimate warming and the recent crisis in real estate has underlined the fragility of tourism in the Cerdagne region of southern France.
Philippe Bachimon, Pierre Dérioz, Mihaela Marc   +2 more
doaj   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

FEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Training Students to do In-Home Behavioral Therapy with Toddlers from Low-Income Families [PDF]

, 2010
The purpose of this project was to develop an internship training program that offered in-home therapy for young children with significant emotional and behavior problems. The children lived in single-parent, low-income homes in unsafe neighborhoods of a
Mattek, Ryan
core   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

INTERNATIONAL MIGRATION, SECOND HOME PROGRAMMES DEVELOPMENT AND MALAYSIA EXPERIENCE

International Journal of Built Environment and Sustainability, 2019
Second homes primarily used for leisure and recreation, which located away from the city. The scenario changed over the years as there are a lot of programmes, namely second home or international migration programmes around the world that promote and ...
Mohd Jamsyeer Khan, Siti Hajar Misnan, Hairul Nizam Ismail   +2 more
doaj   +1 more source

Reviving second homes in tourism sector: the case of Muğla - Datça province [PDF]

, 2011
Türkiye son 20 yılda turizm alanında hızlı bir gelişme kaydetmiş, turist sayısı ve turizm geliri bakımından dünyada ilk on ülke içerisinde yer almayı başarmıştır.
Duman, Teoman, Kozak, Metin
core  

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source