Results 181 to 190 of about 852,308 (302)

Protein Structuromics Reveals a Loop‐Controlled Half‐Open Active Pocket Conformation Throughout Fe(II)/α‐ketoglutarate‐Dependent Dioxygenase Catalytic Cycle

Advanced Science, EarlyView.
This study reveals a conserved half‐open active pocket in Fe(II)/α‐ketoglutarate‐dependent dioxygenases through protein structuromics, distinguished by structural features comprising highly flexible loop elements. Enhanced sampling simulations‐guided mutagenesis experiments elucidated how this flexible loop regulates pocket open/closed conformations ...
Lunjie Wu, Huan Liu, Songyin Zhao, Lei Qin, Jiarui Li, Jun Wang, Zixuan Dai, Jie Gu, Yan Xu, Feiran Li, Yao Nie   +10 more
wiley   +1 more source

Developmental variation in basal ganglia tissue iron, neurocognitive functioning, and impulsivity is associated with substance use trajectories in youth. [PDF]

Nat Commun
Parr AC, Ojha A, Petrie DJ, Calabro FJ, Tervo-Clemmens B, Foran W, Fitzgerald D, Tapert SF, Nooner K, Thompson W, Goldston DB, Clark D, Luna B.   +12 more
europepmc   +1 more source

A Periosteum‐Inspired Janus Piezoelectric Scaffold Using Bioenergetic‐Driven H‐Type Vascularization for Diabetic Bone Regeneration

Advanced Science, EarlyView.
A periosteum‐inspired Janus piezoelectric scaffold converts micromechanical forces into electrical signals and synergizes with controlled resveratrol release. This dual action reprograms endothelial metabolism, drives H‑type vessel formation, and restores bone–vessel coupling in diabetic bone defects.
Kai Wang, Kai Jiang
wiley   +1 more source

Iron in breastfed infants and behavior at 3 years: a randomized trial. [PDF]

Sci Rep
Svensson LK, Chmielewski G, Domellöf M, Konarska Z, Pieścik-Lech M, Späth C, Szajewska H, Chmielewska A.   +7 more
europepmc   +1 more source

The Iron Age landscape of Alcoi Valley, eastern Iberia: Agricultural intensification and sociopolitical dynamics

, 2014
Ignacio Grau Mira
semanticscholar   +1 more source

Femtosecond‐Laser‐Induced Physical Unclonable Random Maze Structure for Storage‐Free Encryption

Advanced Science, EarlyView.
Femtosecond‐laser‐induced gold random maze structures serve as multimodal physical unclonable functions for storage‐free encryption. Their stochastic optical, electrical, and Raman responses are generated by plasmon‐assisted Marangoni formation and converted into AES‐compatible keys without permanent secret‐key storage, offering a portable route toward
Shiru Jiang, Hongliang Li, Shengjie Ma, Sang‐Shin Lee, Lei Wang, Mengyun Hu, Heping Zeng   +6 more
wiley   +1 more source

Maternal anemia across pregnancy in a multi-ethnic tertiary maternity center in a Singaporean population: prevalence, risk factors, and pregnancy outcomes. [PDF]

Front Med (Lausanne)
Peng HMS, Ong SM, Huang H, Yuvaraj H, Lim SK.   +4 more
europepmc   +1 more source

Separating, Demarcating and Accessing Sacred Spaces in the Mediterranean Territories of the Iberian Peninsula during the Second Iron Age

Cet article vise à mieux comprendre les limites des lieux de culte du second âge du Fer en Ibérie, en particulier sur sa façade méditerranéenne, qui constitue l’une des premières composantes essentielles pour appréhender ces espaces sacrés dans leur globalité.
openaire   +1 more source

AI‐Physics‐Experiment Trinity for Integrated Protein Dynamics Modeling

Advanced Science, EarlyView.
This review unites experiments, physics‐based simulations, and AI as a synergistic triad for protein dynamics modeling. It highlights integrative strategies, resolves sampling and forcefield bottlenecks, and outlines challenges and future directions for accurate, interpretable conformational ensemble prediction.
Chen Shi, Minying Low, Peng Xiu, Kresten Lindorff‐Larsen, Yong Wang   +4 more
wiley   +1 more source

Dietary trace mineral intake and risk of all-cause and cardiovascular mortality in population with cardiovascular-kidney-metabolic syndrome stage 0-3: a cohort study. [PDF]

BMC Public Health
Yi C, Li F, Cai J.
europepmc   +1 more source