Results 151 to 160 of about 22,599,037 (316)

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

A Second Life for MAP, a Model Amphipathic Peptide. [PDF]

open access: yesInt J Mol Sci, 2022
Silva S   +4 more
europepmc   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

A Perspective on the Challenges and Prospects of Realizing the Second Life of Retired EV Batteries

open access: yesBatteries
As electric vehicle (EV) adoption continues to surge globally, the question of what to do with retired EV batteries looms large. While these batteries may no longer meet the rigorous demands of automotive use, they often retain a significant portion of ...
Prodip K. Das
doaj   +1 more source

Second-life battery systems for affordable energy access in Kenyan primary schools. [PDF]

open access: yesSci Rep, 2023
Kebir N   +6 more
europepmc   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

On the State of Usability for Lithium–Ion Batteries

open access: yesBatteries
Lithium–ion batteries are well established as traction batteries for electric vehicles. This has led to a growing market for second-life batteries that can be used in applications like home energy storage systems.
Christopher Wett   +4 more
doaj   +1 more source

A Second Life for Seafood Waste: Therapeutical Promises of Polyhydroxynapthoquinones Extracted from Sea Urchin by-Products. [PDF]

open access: yesAntioxidants (Basel), 2023
Melotti L   +8 more
europepmc   +1 more source

Electric vehicles batteries for a circular economy: Second life batteries as stationary storage

open access: yesJournal of Cleaner Production, 2022
Jagruti Thakur   +2 more
semanticscholar   +1 more source

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