Antibody association in solution: cluster distributions and mechanisms
Understanding factors that affect the clustering and association of antibodies molecules in solution is critical to their development as therapeutics. For 19 different monoclonal antibody (mAb) solutions, we measured the viscosities, the second virial ...
Sandi Brudar +10 more
doaj +1 more source
Specific refractive index increments of inulin (SHORT COMMUNICATION) [PDF]
The specific refractive index increments (dn/dc) of inulin in water, at 25°C, were measured at different wavelengths (436, 546 and 589 nm) using a BP-differential refractometer. The dn/dc at the operating wavelength (633 nm) of the laser light scattering
LJUBOMIR A. ILIC +2 more
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Determination of scattering parameters of polyvinyl alcohol by static laser scattering
Static laser scattering (SLS) is one of the most efficient techniques used for the molecular weight determination of polymer. Among of all polymers, polyvinyl alcohol (PVA) polymer was selected. A polystyrene (PS) was used as a standard polymer.
H. Hashim +3 more
doaj +1 more source
In this study, we used sodium chloride (NaCl) to extensively modulate non-specific protein-protein interactions (PPI) of a humanized anti-streptavidin monoclonal antibody class 2 molecule (ASA-IgG2).
Amy Y. Xu +10 more
doaj +1 more source
Optical Kerr and Cotton-Mouton effects in atomic gases: a quantum-statistical study
Theory of the birefringence of the refractive index in atomic diamagnetic dilute gases in the presence of static electric (optical Kerr effect) and magnetic (Cotton-Mouton effect) fields is formulated.
Moszynski, Robert, Skomorowski, Wojciech
core +1 more source
Molecular Origins of Philicity: How Atomic Interactions Determine Miscibility and Diffusivity
Alterations in the atomic philicity, as represented by Lennard–Jones parameters, determine the miscibility of an alkane‐perfluoroalkane system. Some parameters enhance mixing, while others enhance phase separation.We present a computational study on the microscopic origin of molecular philicity, which determines the miscibility and diffusivity of ...
Anna Luisa Upterworth +2 more
wiley +1 more source
Some monoclonal antibodies undergo liquid-liquid phase separation owing to self-attractive associations involving electrostatic and other soft interactions, thereby rendering monoclonal antibodies unsuitable as therapeutics.
Tatsuji Matsuoka +3 more
doaj +1 more source
Effects of Polydispersity on the Phase Behavior of Additive Hard Spheres in Solution
The ability to separate enzymes, nucleic acids, cells, and viruses is an important asset in life sciences. This can be realised by using their spontaneous asymmetric partitioning over two macromolecular aqueous phases in equilibrium with one another ...
Luka Sturtewagen, Erik van der Linden
doaj +1 more source
Streaming potential analysis of hair variation: Ethnicities and environmental exposures
Ethnicity and weathering shape electrokinetic behaviour and particle deposition in hair. ζ‐potential magnitudes ranked Caucasian > Indian > Chinese with no significant root‐tip variations. Deposition patterns generally correlate with ζ‐potential but differ by ethnicity, implicating other factors.
Huijun Phoebe Tham +2 more
wiley +1 more source
MODIFIED NUMERICAL TABLES FOR THE CALCULATION OF NON-SPHERICAL CONTRIBUTION TO SECOND VIRIAL COEFFICIENTS AND THE CORRELATION EQUATIONS OF STATE FOR CO,, CS, AND C6H6 [PDF]
A revised analysis of the effect of long-range nonspherical terms in the intermolecular potential on the second virial coefficient is presented with a preferred Hartree-Fock-Dispersion functional (HFD-C) spherical core treatment of the integrations for ...
doaj

