Results 151 to 160 of about 2,096,986 (304)

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Comparison of classic Sanger and next generation sequencing mitotypes of second world war victims from Konfin I mass grave. [PDF]

Int J Legal Med
Obal M, Zupanič Pajnič I.
europepmc   +1 more source

Identification of human remains from the Second World War mass graves uncovered in Bosnia and Herzegovina. [PDF]

Croat Med J, 2015
Marjanović D, Hadžić Metjahić N, Čakar J, Džehverović M, Dogan S, Ferić E, Džijan S, Škaro V, Projić P, Madžar T, Rod E, Primorac D.   +11 more
europepmc   +1 more source

Art+Politics

, 2011
For the exhibition Art + Politics, students worked closely with the holdings of Gettysburg College\u27s Special Collections and College Archives to curate an exhibition in Schmucker Art Gallery that engages with issues of public policy, activism, war ...
Adlon, Josiah B., Birkenshock, Jenna L., DeBiaso, Francesca S., Egan, Shannon, Francisco, Emily A., Glass, Shelby P., Goodall, Hillary B., Hilands, Megan E., Parrish, Colleen L., Reynolds, Molly E., Sheridan, Tessa M.   +10 more
core  

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Splenic Modulation of Plasmodium vivax Relapses and Hypnozoite Activation during the Second World War? [PDF]

Am J Trop Med Hyg
Shanks GD.
europepmc   +1 more source

War on fear: Solly Zuckerman and civilian nerve in the Second World War. [PDF]

Hist Human Sci, 2012
Burney I.
europepmc   +1 more source

The new role of some key peripheral countries after the fall of the Berlin wall. The case of Democratic Republic of Congo [PDF]

The first international african war is going on. From august 1998 on 2.5 million people have been killed directly or indirectly in this media-silent war 1, this is almost one tenth of all 'casualties' incurred by the Soviet Union during the second world ...
Marysse, Stefaan
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Bart van der Boom, ‘Wij weten niets van hun lot’. Gewone Nederlanders en de Holocaust

BMGN: Low Countries Historical Review, 2012
Friso Wielenga
doaj   +1 more source