Results 131 to 140 of about 1,145,423 (310)

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

Professional Training of Human Resources [PDF]

open access: yes
Each organization has a human capital which resides in the knowledge and experience of its own employees, in their professional competence. For the purpose of using this capital as efficiently as possible in the process of carrying out working tasks, it ...
Mioara NEAMTU
core  

Correlation, price discovery and co-movement of ABS and equity [PDF]

open access: yes, 2005
Asset-backed securitization (ABS) has become a viable and increasingly attractive risk management and refinancing method either as a standalone form of structured finance or as securitized debt in Collateralized Debt Obligations (CDO).
Jobst, Andreas A.
core  

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

Three-dimensional inviscid analysis of radial turbine flow and a limited comparison with experimental data [PDF]

open access: yes
The three-dimensional inviscid DENTON code is used to analyze flow through a radial-inflow turbine rotor. Experimental data from the rotor are compared with analytical results obtained by using the code. The experimental data available for comparison are
Choo, Y. K., Civinskas, K. C.
core   +1 more source

HAVE ECONOMIC REFORMS PAID-OFF? GENDER OCCUPATIONAL INEQUALITY IN THE NEW MILLENNIUM IN EGYPT [PDF]

open access: yes, 2008
This study considers the impact of over a decade of structural adjustment policies in Egypt on gender wage and occupational inequality. Using newly released Labor Force Sample Surveys (LFSS) for the years 2000-2004, a slight drop in public sector ...
El-Hamidi, Fatma, Said, Mona
core  

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

open access: yesMolecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard   +12 more
wiley   +1 more source

Taurine priming improves redox balance, osmotic adjustment, and nutrient acquisition to lessen phytotoxic effects of neutral and alkaline salts on pea (Pisum sativum L.)

open access: yesPlant Signaling & Behavior
Taurine (TAR) intricately mediates a plethora of physiological processes. This investigation aimed to elucidate the impact of TAR (50, 100, 150, and 200 mg L−1) seed priming on redox homeostasis, glutathione metabolism, photosynthetic efficiency, osmotic
Umer Farooq   +6 more
doaj   +1 more source

Psychological adjustment challenges among first-year university students: Crucial link between psychological health and academic success in higher education

open access: yesInternational Journal of Studies in Psychology
This study investigates the psychological adjustment challenges faced by first-year students at a selected University in Namibia and their impact on first-year university students’ academic performance. The study aimed to understand first-year university
Anna Niitembu Hako   +2 more
doaj   +1 more source

Screening for lung cancer: A systematic review of overdiagnosis and its implications

open access: yesMolecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz   +12 more
wiley   +1 more source

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