Results 171 to 180 of about 1,145,423 (310)

NICE DSU Technical Support Document 3: Heterogeneity: Subgroups, Meta-Regression, Bias and Bias-Adjustment [PDF]

, 2011
Ades, A E, Dias, Sofia, Sutton, Alex J, Welton, Nicky J   +3 more
core   +2 more sources

Effect of Meditation on Adjustment of Secondary School Students

International Journal For Multidisciplinary Research
In today’s competitive world is growing world where the competition in almost every field which creates its own stress and disturbances, it is important to have good health for better performance. Meditation is a good way to reach a state of mental equanimity where responses to favorable or unfavorable external events are well under the individual’s ...
openaire   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Comorbid Anxiety and Depression in Hyperacusis and Misophonia. Reply to Jastreboff, P.J. Comment on "Rodrigues, A.L.M.; Aazh, H. Psychiatric Comorbidities in Hyperacusis and Misophonia: A Systematic Review. <i>Audiol. Res</i>. 2025, <i>15</i>, 101". [PDF]

Audiol Res
Aazh H, Rodrigues ALM.
europepmc   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Coronary anatomy detects, ischemia predicts: Real-world insights from the Nancy ischemia registry. [PDF]

Int J Cardiol Heart Vasc
Chati Z, Benzaghou N, Balaj C, Tissier S.   +3 more
europepmc   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Medication Adherence in the Glycemia Reduction Approaches in Diabetes: A Comparative Effectiveness Study (GRADE). [PDF]

Diabetes Care
Gonzalez JS, Wen H, Butera NM, Uschner D, Krause-Steinrauf H, Gramzinski MR, Wexler DJ, Petrovitch H, Hoogendoorn CJ, Crespo-Ramos G, Presley C, Fattaleh B, Lagari V, Walker EA, Cherrington AL, GRADE Research Group* .   +15 more
europepmc   +1 more source

Lateral migration of hillcrests in response to channel incision in soil-mantled landscapes [PDF]

, 2005
Anderson, Andrews, Benda, Bishop, Bras, Brimhall, Burbank, Chen, Crosby, Culling, David Jon Furbish, Densmore, Dietrich, Fernandes, Finlayson, Furbish, Gabet, Gabet, Hack, Harbor, Hasbargen, Heimsath, Heimsath, Heimsath, Heimsath, Howard, Howard, Howard, Jyotsna, Kirchner, Kirkby, Kobor, Mather, Matmon, McKean, Meigs, Meyerhof, Mudd, Pelletier, Reneau, Riebe, Roering, Roering, Roering, Simon Marius Mudd, Sklar, Small, Smith, Snyder, Tucker, Tucker, van der Beek, Whipple, Whipple, Willgoose, Young, Young, Zaprowski   +57 more
core   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source