Results 41 to 50 of about 359,195 (267)

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Executive Function and Resilience as Mediators of Adolescents’ Perceived Stressful Life Events and School Adjustment

Frontiers in Psychology, 2019
This study investigated psychological mechanisms underlying the relationship between stressful life events and school adjustment in Chinese adolescents.
Yuqing Zhang, Yuqing Zhang, Xing Zhang, Liwei Zhang, Cheng Guo, Cheng Guo   +5 more
doaj   +1 more source

Sexual activity based fears during pregnancy, sexual function and dyadic adjustment in couples who are expecting their first child

Journal of Psychosomatic Obstetrics and Gynecology, 2022
Purpose: Sexual activity based fears during pregnancy are common, but very few studies have examined their association with relationship variables. Secondary analysis of associations between these fears during pregnancy and both partners’ sexual function
Catherine de Pierrepont, Audrey Brassard, Katherine Bécotte, Isabelle Lessard, Viola Polomeno, Katherine Péloquin   +5 more
doaj   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Improving Psychological Adjustment of the Sexually Abused In-school Adolescents in Nigeria: The Roles of Emotional Stability, Social Anxiety, and Self-Esteem [PDF]

E-Journal of Humanities, Arts and Social Sciences
The researchers considered examining the psychological adjustment process of sexually abused adolescents rather than dwelling on the causes. This study, therefore, examined emotional stability, social anxiety, and self-esteem as correlates of ...
Adewuyi Habeeb Omoponle, Veronica Dwarika   +1 more
doaj   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

Social Adjustment among in-School Adolescents with Learning Disabilities: Do Parental Socioeconomic Status and Peer Influence Play Any Role?

Al Ibtida: Jurnal Pendidikan Guru MI
Social adjustment, a crucial aspect of everyone’s life, is needed to cope with one’s engagement with others in society and overall social life. However, reports have shown that many in-school adolescents, particularly in Oyo State secondary schools ...
Temilade Silifatu Ayo, Kelechi Uchemadu Lazarus   +1 more
doaj   +1 more source

EMPIRICAL ASSESSMENT OF THE GROWTH RATE OF MAIZE PRODUCTION IN THE PRE - SAP, SAP AND POST - SAP PERIODS IN NIGERIA [PDF]

Russian Journal of Agricultural and Socio-Economic Sciences, 2012
This study was carried out to provide empirical evidence on the growth rates of maize production in three sub - periods in Nigeria namely pre - Structural Adjustment Programme period, Structural Adjustment Program period and post - Structural Adjustment ...
Oyinbo Oyakhilomen, Yusuf Dodo Emmanuel
doaj