Results 71 to 80 of about 1,162,640 (307)
ABSTRACT Objective To compare the efficacy and safety of roxarestat versus recombinant human erythropoietin (rhEPO) in the management of renal anemia in patients undergoing maintenance hemodialysis. Methods This was a prospective, open‐label, randomized controlled trial.
Lingling Chen, Junjie Zhu, Qiaonan Ge
wiley +1 more source
As the COVID-19 outbreak is rapidly spreading all over the world, it’s secondary consequences will negatively affect both societies and individuals. The target group, expected to be exposed to the secondary negative consequences most intensely during the
İsmail Seçer +2 more
doaj +1 more source
Adjusting for observational secondary treatments in estimating the effects of randomized treatments [PDF]
In randomized clinical trials, for example, on cancer patients, it is not uncommon that patients may voluntarily initiate a secondary treatment postrandomization, which needs to be properly adjusted for in estimating the "true" effects of randomized treatments.
Min, Zhang, Yanping, Wang
openaire +2 more sources
Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
MARKET ADJUSTMENT INSIGHTS: PRIMARY VS. SECONDARY DATA [PDF]
Producers, researchers, and policy makers have an interest in market effects from meatpacking plant closings and openings. This paper presents results from a study taking a dual approach to determining impacts from an anticipated hog slaughtering plant ...
Hornung, Jonathan T., Ward, Clement E.
core +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
This study aims to determine to what extent prior academic performance (secondary school Grade Point Average (GPA) and Ethiopian University Entrance Exam (EUEE) scores) and the psychosocial factors (academic motivation, self-esteem, academic self ...
Adugna Bersissa Merdassa
doaj +1 more source
Structural biology of ferritin nanocages
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
The G-protein Coupled Receptor GPR8 Regulates Secondary Metabolism in Trichoderma reesei
Changing environmental conditions are of utmost importance for regulation of secondary metabolism in fungi. Different environmental cues including the carbon source, light and the presence of a mating partner can lead to altered production of compounds ...
Wolfgang Hinterdobler +5 more
doaj +1 more source

