Results 201 to 210 of about 7,990,793 (300)

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

Secondary Analysis of a Brief Parent-Implemented NDBI on Activity-Engaged Triadic Interactions Within Mother-Child Dyads. [PDF]

Behav Sci (Basel)
Ousley C, Szydlik T, Neiman S, Elliott N.   +3 more
europepmc   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna   +12 more
wiley   +1 more source

Predictors of PTSD Symptom Reduction in a Secondary Analysis of a Randomized Controlled Clinical Trial. [PDF]

J Clin Med
Smith TC, Smith B, Hsiao AF, Munoz A, Aden C, Lai-Trzebiatowski J, Jung M, Murphy TJ, Hollifield M.   +8 more
europepmc   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

Social drivers and pediatric injury outcomes in Northern Tanzania: A prospective pediatric injury registry secondary analysis. [PDF]

PLOS Glob Public Health
Tedford NJ, Mitao M, Peter TA, Minja L, de Oliveira GN, Mingo R, Nkini G, Staton C, Vissoci JRN, Mmbaga BT, Keating EM.   +10 more
europepmc   +1 more source

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

Aging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss, Alexis C. Wardell, Allison M. Deal, Kirsten A. Nyrop, Allison Ross, Yara G. Abdou, Jeffrey D. Aldrich, Lisa A. Cary, E. Claire Dees, Katherine E. Reeder‐Hayes, Emily M. Ray, Natalia Mitin, Denis Tsygankov   +12 more
wiley   +1 more source

Association Between Ipsilateral Stroke and Nonstenotic (<50%) Carotid Disease: Secondary Analysis From the AcT Trial. [PDF]

J Am Heart Assoc
Ignacio KHD, Nagendra S, Bala F, Alhabli I, Kaveeta C, Tanaka K, Baguley E, Poulin T, Sjonnesen K, Horn M, Dowlatshahi D, Shamy M, Khosravani H, Swartz RH, Catanese L, Tkach A, Buck B, Field T, Hunter G, Shankar J, Sajobi T, Menon BK, Almekhlafi MA, Ganesh A, Singh N.   +24 more
europepmc   +1 more source

An alternative treatment of secondary products in input-output analysis. [PDF]

Chakraborty, D., Raa, M.H. ten, Small, J.A.   +2 more
core   +1 more source

Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon, Nathalie Picard, Valeria d'Andrea, Enchi Chang, Joseph Leffler, Eleonora Centofante, Matthew Taylor, Francesca Bardi, Francesca Cavicchiolo, Takao K. Hensch, Stefano Panzeri, Chinfei Chen, Michela Fagiolini   +12 more
wiley   +1 more source