Results 241 to 250 of about 8,095,731 (348)

Opening Pandora's box in the emergency room: a secondary analysis of existential needs from observational, registered nurse, and patient perspectives. [PDF]

BMC Nurs
Pavedahl V, Meranius MS, Muntlin Å.
europepmc   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Quality of life after preoperative home-based exercise training in patients with lung cancer: a secondary analysis. [PDF]

J Thorac Dis
Pimenta S, Machado P, Silva CG, Garcia AL, Nogueira T, Silva S, Dos Santos CL, Martins MV, Canha A, Oliveiros B, Martins RA, Cruz J.   +11 more
europepmc   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Treatment limitation decision in delirium: a secondary analysis of a prospective observational study. [PDF]

BMC Med Ethics
Montaut V, Bergqvist L, Zender H, Donzé J, John G.   +4 more
europepmc   +1 more source

An alternative treatment of secondary products in input-output analysis. [PDF]

Chakraborty, D., Raa, M.H. ten, Small, J.A.   +2 more
core   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Determinants of adolescent pregnancy in Zambia: A secondary data analysis of 2018 Zambia Demographic and Health Survey [PDF]

Whiteson Mbele, Babucarr Jassey
openalex   +1 more source

Thrombelastography as a Predictive Tool for Thromboembolic Events After Extremity Trauma: A Secondary Analysis of PREVENT-CLOT. [PDF]

JB JS Open Access
Mayfield CK, O'Hara NN, Schneider PS, Castillo RC, O'Toole RV, Frey KP, Obremskey W, Stein DM, Firoozabadi R, Warner SJ, Karunakar MA, Gary JL.   +11 more
europepmc   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

FEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento, Danniel Pereira‐Figueiredo, Gabriella Grossi de Lima Dias, Gabriel Ferreira dos Santos, Mariana Rodrigues Pereira, Rafael Brito, Karin C Calaza   +6 more
wiley   +1 more source